Results 211 to 220 of about 218,218 (394)

Spatial Transcriptomic Analysis Reveals HDAC Inhibition Modulates Microglial Dynamics to Protect Against Ischemic Stroke in Mice

Glia, EarlyView.
Spatial transcriptomic analysis unravels the mechanisms by which HDACi ameliorates neuroinflammation and enhances neuroprotection by modulating the expression of microglial transcriptomes in the ischemic mouse brain. ABSTRACT Ischemic stroke significantly contributes to global morbidity and disability through a cascade of neurological responses ...
Kevin Jayaraj, Ritesh Kumar, Sukanya Shyamasundar, Thiruma V. Arumugam, Jai S. Polepalli, S. Thameem Dheen   +5 more
wiley   +1 more source

Regulation of the Synthesis of Choline- O -Acetyltransferase and Thymidylate Synthetase in Mouse Neuroblastoma in Cell Culture [PDF]

, 1971
Roger N. Rosenberg, Larry Vandeventer, Laura De Francesco, Morris Friedkin   +3 more
openalex   +1 more source

Acetylseco hemicholinium-3, a new choline acetyltransferase inhibitor useful in neuropharmacological studies [PDF]

, 1973
E.F. Domino, M. Mohrman, Ann Wilson, Vernon B. Haarstad   +3 more
openalex   +1 more source

A computational study exploring echinoderm-derived compounds for inhibition of aminoglycoside acetyltransferases. [PDF]

PLoS One
Alanzi AR, Alqahtani MJ, Alqahtani JH, Alharbi HA.   +3 more
europepmc   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Emerging role of N-acetyltransferase 10 in diseases: RNA ac4C modification and beyond. [PDF]

Mol Biomed
Jiao L, Si Y, Yuan Y, Lei X, Jiang Q, Yang L, Mao W, Ying B, Ma L, Sun T.   +9 more
europepmc   +1 more source

Distribution of chloramphenicol acetyltransferase and chloramphenicol-3-acetate esterase among Streptomyces and Corynebacterium.

, 1977
Hirofumi Nakano, Yuji Matsuhashi, TOMIO TAKEUCHI, HAMAO UMEZAWA   +3 more
openalex   +2 more sources

Aminoglycoside 6'-N acetyltransferase production by an isolate of Pseudomonas maltophilia [PDF]

, 1978
B. A. King, Kevin Shannon, Ian Phillips
openalex   +1 more source

Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions

International Journal of Cancer, EarlyView.
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner, Jayant Y. Gadrey, Scott A. Armstrong, Michael W. M. Kühn   +3 more
wiley   +1 more source

Lysine Acetyltransferase 8: A Target for Natural Compounds in Cancer Therapy. [PDF]

Int J Mol Sci
Wang L, Zhao L, Lan X, Zhu M, Tan Y, Luo H, Wu D.   +6 more
europepmc   +1 more source