Results 221 to 230 of about 218,218 (394)

Enhancer‐dependent gene regulation in space, time, and malignancies

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Control of cell‐type‐specific gene activation requires the coordinated activity of distal regulatory elements, including enhancers, whose inputs must be temporally integrated. Dysregulation of this regulatory capacity, such as aberrant usage of enhancers, can result in malignant transformation of cells.
Belinda Blum   +2 more
wiley   +1 more source

Epigenetic reprogramming in multiple myeloma—Challenges and opportunities

open access: yesInternational Journal of Cancer, EarlyView.
Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar   +2 more
wiley   +1 more source

Spectrophotometric Assay for Amikacin Using Purified Kanamycin Acetyltransferase

open access: green, 1979
Emanual Scarbrough   +2 more
openalex   +1 more source

Spermidine induces autophagy by inhibiting the acetyltransferase EP300

open access: yesCell Death and Differentiation, 2014
F. Pietrocola   +18 more
semanticscholar   +1 more source

Maternal gut microbiota‐derived daidzein prevents osteoporosis in female offspring following prenatal prednisone exposure

open access: yesiMeta, EarlyView.
Prenatal prednisone therapy (PPT)/prenatal prednisone exposure (PPE) induces long bone dysplasia, reduced peak bone mass (PBM), and increased osteoporosis susceptibility in female offspring. Maternal gut microbiota metabolite daidzein (DAI) mediates PPE‐induced osteoporosis susceptibility in female adult offspring.
Chi Ma   +13 more
wiley   +1 more source

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