Results 271 to 280 of about 218,218 (394)

αTAT1 is the major α-tubulin acetyltransferase in mice

open access: yesNature Communications, 2013
Nereo Kalebic   +5 more
semanticscholar   +1 more source

Probing Enzymatic Acetylation Events in Real Time With NMR Spectroscopy: Insights Into Acyl‐Cofactor Dependent p300 Modification of Histone H4

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Lysine acylation is a rapidly expanding class of post‐translational modifications with largely unexplored functional roles; the study of acylations beyond acetylation is especially impeded by limited methods for their preparation, detection, and characterization in vitro. We previously reported a nuclear magnetic resonance (NMR)‐based approach
Sophia M. Dewing, Scott A. Showalter
wiley   +1 more source

Binding of RHOA G17V to p300 enhances its HAT activity: a new mechanism of epigenetic deregulation in TFH lymphoma. [PDF]

open access: yesBlood Adv
Vallois D   +7 more
europepmc   +1 more source

Multifunctional Bioactive Dual‐Layered Nanofibrous Matrix for Effective Breast Cancer Therapy and Enhanced Wound Healing

open access: yesSmall, EarlyView.
The multifunctional dual‐layered nanomatrix addresses post‐surgical challenges in triple‐negative breast cancer by integrating shape control, wound adherence, and tunable drug release. It delivers anticancer and antibacterial therapies through chemodynamic therapy, photothermal therapy, ferroptosis, cuproptosis, and sustained chemotherapy, enhancing ...
Sungyun Kim   +8 more
wiley   +1 more source

Cardiac-specific overexpression of PRMT5 exacerbates pressure overload-induced hypertrophy and heart failure. [PDF]

open access: yesJ Biomed Sci
Katanasaka Y   +10 more
europepmc   +1 more source

A Smart Functional Microneedle, Tethered with Neuropeptide S and Tissue Inhibitor of Metalloproteinases, Promotes Skin, Vascular, and Nerve Regeneration for Chronic Diabetic Skin Wound Healing

open access: yesSmall Structures, EarlyView.
A smart functional microneedle system, tethered with NPS and TIMP, which not only promotes diabetic wound healing and tissue remodeling at the injury site but also demonstrates the ability to dynamically and responsively release NPS and TIMP as needed, offering a potential therapeutic approach for clinical translation is presented. Increased expression
Xiaojie Lu   +5 more
wiley   +1 more source

Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility.

open access: yesCell Metabolism, 2012
D. Muoio   +15 more
semanticscholar   +1 more source

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