Results 301 to 310 of about 218,218 (394)

Non‐canonical nitric oxide signalling and DNA methylation: Inflammation induced epigenetic alterations and potential drug targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract DNA methylation controls DNA accessibility to transcription factors and other regulatory proteins, thereby affecting gene expression and hence cellular identity and function. As epigenetic modifications control the transcriptome, epigenetic dysfunction is strongly associated with pathological conditions and ageing.
Christopher H. Switzer
wiley   +1 more source

Modulation of the substrate preference of a MYST acetyltransferase by a scaffold protein. [PDF]

open access: yesJ Biol Chem
Sengupta RN   +11 more
europepmc   +1 more source

Dauricine Overcomes Osimertinib Resistance in Lung Cancer by Inducing Ferroptosis via Stabilizing SAT1

open access: yesCancer Science, EarlyView.
Our study explores the potential of dauricine, a bioactive compound from Menispermum dauricum, to overcome osimertinib resistance in lung cancer. We demonstrate that dauricine, when combined with osimertinib, induces ferroptosis in resistant lung cancer cells by stabilizing SAT1, a key enzyme in oxidative stress regulation.
Biying Men   +16 more
wiley   +1 more source

Nerve growth factor (NGF) [PDF]

open access: yes, 1989
Azzi, Angelo   +6 more
core  

Genetic Association of Primary Angle‐Closure Glaucoma and Disease Progression

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To investigate single‐nucleotide polymorphisms (SNPs) reported in the largest up‐to‐date systematic review and meta‐analysis on primary angle‐closure disease (PACD), on their associations with primary angle‐closure glaucoma (PACG) and disease progression.
Yu Jing Liang   +6 more
wiley   +1 more source

Regulation of mild moxibustion on non-neuronal cholinergic system in ulcerative colitis rats. [PDF]

open access: yesJ Tradit Chin Med
Guangbin P   +10 more
europepmc   +1 more source

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