Results 311 to 320 of about 218,218 (394)

S1 mapping of the pC194 encoded chloramphenicol acetyltransferase gene inBacillus subtilis

, 1988
Heinrich Leonhardt, Juan C. Alonso
openalex   +2 more sources

Further Exploring the TRRAP Genotype–Phenotype Correlations: Report of Three New Patients With A Focus on Skeletal Anomalies

Clinical Genetics, EarlyView.
We report on the clinical characteristics of three new patients with pathogenic TRRAP variants expanding the syndrome's phenotype. In order to investigate the TRRAP potential involvement in skeletal development, osteoclastogenesis in Patient 1 was evaluated and TRRAP expression in osteoclasts and osteoblasts were analyzed.
Chiara Minotti, Sara Terreri, Andrea Del Fattore, Francesca Romana Lepri, Rosario Ruta, Maria Iascone, Laura Pezzoli, Maria Lisa Dentici, Antonio Novelli, Michelina Armando, Daniela Longo, Giuseppe Novelli, Domenico Barbuti, Andrea Bartuli, Ugo Cavallari, Ludovico Graziani, Maria Cristina Digilio, Lorenzo Sinibaldi   +17 more
wiley   +1 more source

Streptococcus pneumoniae serotype 33H: a novel serotype with frameshift mutations in the acetyltransferase gene wciG. [PDF]

Pneumonia (Nathan)
Manna S, Ortika BD, Werren JP, Pell CL, Gjuroski I, Lo SW, Hinds J, Tundev O, Dunne EM, Gessner BD, Russell FM, Mulholland EK, Mungun T, von Mollendorf C, Bentley SD, Hilty M, Ravenscroft N, Satzke C.   +17 more
europepmc   +1 more source

Membraneless Organelles and Phase Separation in Tumours: Mechanisms and Prospects

Cell Proliferation, EarlyView.
The Salient and Novel Findings: This article summarises the latest research advancements in phase separation within tumours, with a particular focus on the role and molecular mechanisms of liquid–liquid phase separation (LLPS) in tumour progression.
Hao Yang, Zhong Chu, Shuwen Han, Yuefen Pan   +3 more
wiley   +1 more source

<i>aac(6')-Iaq</i>, a novel aminoglycoside acetyltransferase gene identified from an animal isolate <i>Brucella intermedia</i> DW0551. [PDF]

Front Cell Infect Microbiol
Lin N, Xu W, Huang D, Liu C, Lu J, Zhu M, Bao Q, Pan W.   +7 more
europepmc   +1 more source

Lactate and Lactylation in AKI‐to‐CKD: Epigenetic Regulation and Therapeutic Opportunities

Cell Proliferation, EarlyView.
ABSTRACT Lactate is not only a byproduct of glycolysis, but is also considered an energy source, gluconeogenic precursor, signalling molecule and protein modifier during the process of cellular metabolism. The discovery of lactylation reveals the multifaceted functions of lactate in cellular metabolism and opens new avenues for lactate‐related research.
Yi Hou, Dongwei Liu, Zuishuang Guo, Cien Wei, Fengyu Cao, Yue Xu, Qi Feng, Fengxun Liu   +7 more
wiley   +1 more source

In vitro models of valproic acid to assess neurodevelopmental toxicity: A scoping review

Epilepsia, EarlyView.
Abstract Valproic acid (VPA) is a first‐line antiseizure medication (ASM) that is highly efficacious for treating generalized and focal epilepsy disorders. Unfortunately, due to its strong association with teratogenic effects culminating in fetal valproate spectrum disorder (FVSD), which may include neurocognitive and neurobehavioral deficits, the drug
Daniel Sandvik, Elena Vianca, Alison Anderson, Muhammad Shahid Javaid, Terence J. O'Brien, Ana Antonic‐Baker   +5 more
wiley   +1 more source

Acetyltransferase NAT10 inhibits T-cell immunity and promotes nasopharyngeal carcinoma progression through DDX5/HMGB1 axis. [PDF]

J Immunother Cancer
Xie H, Zhang K, Yin H, Zhang S, Pan S, Wu R, Han Y, Xu Y, Jiang W, You B.   +9 more
europepmc   +1 more source

Enzyme response to thyrotoxicosis and hypothyroidism in human liver and muscle [PDF]

, 1972
Bachmaier, B., Kiefhaber, P., Nolte, J., Pette, D., Schneider, H., Scriba, Peter Christian   +5 more
core  

Medial septum parvalbumin‐expressing inhibitory neurons are impaired in a mouse model of Dravet syndrome

Epilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a severe neurodevelopmental disorder caused by pathogenic variants in the SCN1A gene, which encodes the voltage‐gated sodium channel Nav1.1 α subunit. Experiments in animal models of DS—including the haploinsufficient Scn1a+/− mouse—have identified impaired excitability of interneurons in the hippocampus and ...
Limei Zhu, Yiannos Demetriou, Joseph Barden, Juan Disla, Meiling Zhao, Joanna Mattis   +5 more
wiley   +1 more source