Results 321 to 330 of about 218,218 (394)

Advances of NAT10 in diseases: insights from dual properties as protein and RNA acetyltransferase. [PDF]

Cell Biol Toxicol
Xiao B, Wu S, Tian Y, Huang W, Chen G, Luo D, Cai Y, Chen M, Zhang Y, Liu C, Zhao J, Li L.   +11 more
europepmc   +1 more source

Epigenetic control of cell identities from epiblast to gastrulation

The FEBS Journal, EarlyView.
In this review, we present and contextualize current knowledge about the roles of epigenetic modifiers during the development of mouse epiblast to gastrulation stage. The epigenetic regulation of enhancer and promoter elements by DNA methylation, histone modifications, and chromatin accessibility in concert with lineage‐specific transcription factors ...
Katrin M. Schüle, Simone Probst
wiley   +1 more source

Lysine acetyltransferase 5 contributes to diabetic retinopathy by modulating autophagy through epigenetically regulating autophagy-related gene 7.

Cytojournal
Gao Q, Lai Y, He S, Wang Y, Zhang G, Zhu X, Zhuang S.   +6 more
europepmc   +1 more source

Whole-Genome Analysis of <i>Paenibacillus campinasensis</i> from Blood of a Hand-Foot-Mouth Patient. [PDF]

Infect Drug Resist
Yu X, Lin J, Jiang W, Zhu T, Lin X, Liu X, Zeng Y.   +6 more
europepmc   +1 more source

Interaction of TFAP2A with the Ku70/80 complex is crucial for HIF‐dependent activation of hypoxia‐inducible genes

The FEBS Journal, EarlyView.
Under normoxic conditions, the SUMOylated fraction of TFAP2A cannot interact with the Ku70/Ku80 complex, nor it can bind to chromatin. The unSUMOylated fraction pre‐occupies the chromatin of a subset of hypoxia‐induced genes together with the Ku70/Ku80 complex for basal euchromatin formation. Under hypoxic conditions, the SUMOylation equilibrium shifts
Amalia Kanoura, Antonis Giakountis, Chrysa Filippopoulou, Angeliki Karagiota, George Stamatakis, Martina Samiotaki, George Panayotou, George Simos, Georgia Chachami   +8 more
wiley   +1 more source

Role of NAT10-mediated ac⁴C acetylation of ENO1 mRNA in glycolysis and apoptosis in non-small cell lung cancer cells. [PDF]

BMC Pulm Med
Yuan Y, Li N, Zhu J, Shao C, Zeng X, Yi D.   +5 more
europepmc   +1 more source

Stress exposure in the mdx mouse model of Duchenne muscular dystrophy provokes a widespread metabolic response

The FEBS Journal, EarlyView.
A targeted mass spectrometry‐based metabolomics assay was conducted to identify the impact of stress exposure on the regulation of biological stress pathways in the mdx mouse model of Duchenne muscular dystrophy. We demonstrated a broad shift in the circulating stress‐relevant plasma metabolome associated with stressful scruff handling that was ...
Erynn E. Johnson, James M. Ervasti
wiley   +1 more source

Association between NAT10 gene rs8187 G > A polymorphism and Wilms tumor susceptibility in Chinese Han children: a five-center case-control study. [PDF]

BMC Cancer
Deng C, Zhu J, Duan F, Zhang W, Zhou H, Li S, Zhang J, Cheng J, Fu W, He J, Niu H, Hua RX.   +11 more
europepmc   +1 more source

Protein succinylome analysis identifies citrate synthase as a central regulator of osteoclast metabolic activity

The FEBS Journal, EarlyView.
RANKL treatment induces expression of the aconitate decarboxylase (ACOD1) in differentiating osteoclasts, which increases succinate levels. The initially high expression of ACOD1 decreases towards the end of differentiation when the levels of the desuccinylase SIRT5 increase. Succinylation of citrate synthase (CS) was detected exclusively in stimulated
Dayoung Yu, Yue Gao, Marcin Luzarowski, Elisabeth Seebach, Thomas Heitkamp, Michael Börsch, Thomas Ruppert, Katharina F. Kubatzky   +7 more
wiley   +1 more source

Three ARID proteins involved in chromatin remodeling PEAT complexes are targeted by the Ralstonia solanacearum effector PopP2 and contribute to bacterial wilt disease. [PDF]

Plant J
Monge-Waleryszak L, Girard M, Carcagno M, Culerrier R, Vicédo C, Martinez Y, Vérin C, Couté Y, Pacquit V, Deslandes L.   +9 more
europepmc   +1 more source