Results 101 to 110 of about 7,605,068 (272)

Clinical acid-base pathophysiology: disorders of plasma anion gap. [PDF]

, 2003
The plasma anion gap is a frequently used parameter in the clinical diagnosis of a variety of conditions. The commonest application of the anion gap is to classify cases of metabolic acidosis into those that do and those that do not leave unmeasured ...
Moe, Orson W, Fuster, Daniel Guido
core   +1 more source

Acid-Base Disorders in the Critically Ill Patient. [PDF]

Clin J Am Soc Nephrol, 2023
Achanti A, Szerlip HM.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Metabolic Disorders of Acid - Base Balance [PDF]

, 2018
Bakalářská práce se v první části věnuje acidobazické rovnováze včetně jejích poruch. Práce se zabývá respiračními i metabolickými poruchami. Kapitola metodika se věnuje samotnému vyšetření. Zahrnuje principy měření parametrů pH, pCO2, pO2.
Štych Patrik
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Electrolyte and Acid-Base Disorders Associated with Cancer Immunotherapy. [PDF]

Clin J Am Soc Nephrol, 2022
Uppal NN, Workeneh BT, Rondon-Berrios H, Rondon-Berrios H, Jhaveri KD.   +4 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Comparison of three methods of evaluation of acid-base disorders in pediatric patients requiring intensive care

, 2010
Objetivo: comparar el rendimiento diagnóstico de los métodos tradicional, brecha aniónica corregida y de Stewart, para el diagnóstico de los trastornos ácido-base e hiperlactatemia en niños críticos.
Betancur Franco, Linda Andrea
core  

Revisiting Stewart's Approach toward Assessment of Unidentified or Complex Acid-Base Disorders. [PDF]

Indian J Crit Care Med, 2022
Gopaldas JA.
europepmc   +1 more source