Results 111 to 120 of about 7,605,068 (272)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Acid-Base Solutions

, 2014
Ensino Médio::QuímicaConhecimentos sobre ácidos, bases, pH e equilíbrio químicoA simulação permite explorar propriedades como pH, condutividade elétrica de soluções de ácidos e bases fortes e fracas, além de verificar as concentrações de equilíbrio das ...
Loeblein, Patricia, Perkins, Kathy, Malley, Chris, Parson, Robert, Lancaster, Kelly   +4 more
core  

ACID AND BASE DISORDERS IN DIARRHOEA AND VOMITING:STUDY IN 805 INFANTS WITH GASTROENTERITIS [PDF]

Acta Medica Iranica, 1996
This study was carried out on 1330 infants, from one to 24 months old, suffering from diarrhoea and moderate to severe dehydration who were hospitalized in Bahrami childrens' hospital over a period of eleven months. Fifteen percent of them had signs
Z. Nowrouzi
doaj  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Acid-Base Solutions

, 2012
Ensino Médio::QuímicaConhecimentos sobre ácidos, bases, pH e equilíbrio químicoA simulação permite explorar propriedades como pH, condutividade elétrica de soluções de ácidos e bases fortes e fracas, além de verificar as concentrações de equilíbrio das ...
Loeblein, Patricia, Perkins, Kathy, Malley, Chris, Parson, Robert, Lancaster, Kelly   +4 more
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Electrolyte and Acid-Base Disorders Triggered by Aminoglycoside or Colistin Therapy: A Systematic Review. [PDF]

Antibiotics (Basel), 2021
Scoglio M, Bronz G, Rinoldi PO, Faré PB, Betti C, Bianchetti MG, Simonetti GD, Gennaro V, Renzi S, Lava SAG, Milani GP.   +10 more
europepmc   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

The frequency of acid-base disorders on admission to the intensive care and its association with in-hospital outcome, Cape Town, South Africa: a retrospective cohort study. [PDF]

Pan Afr Med J, 2022
Sithole N, Lalla U, Davids MR, Chothia MY.   +3 more
europepmc   +1 more source