Results 171 to 180 of about 205,592 (306)

Macro-micromorphological, anatomical, and phytochemical characterization of Cucumis melo var. agrestis Naudin: a potential source of natural antioxidants. [PDF]

Sci Rep
Shehata FA, Hamdy R, Garf IE, Megahed EM.   +3 more
europepmc   +1 more source

Senomorphic Small Extracellular Vesicles Delivered by a Tissue‐Adhesive α‐Lipoic‐Acid Hydrogel Enable Immuno‐Rejuvenation for Bone‐Tendon Interface Regeneration

Advanced Science, EarlyView.
This work identifies M1 macrophage‐mediated inflammation as a key driver of BMSC senescence and bone microstructural deterioration at the enthesis. A tissue‐adhesive hydrogel delivering senomorphic small extracellular vesicles suppresses this inflammatory‐senescent cascade and enhances BMSC resilience by inhibiting the cGAS‐STING‐NF‐κB pathway.
Lingzhi Kong, Wei Song, Wencai Liu, Hui Xu, Yuhao Yu, Xinyue Yang, Haiyan Li, Yanlun Zhu, Yaohua He   +8 more
wiley   +1 more source

Dynamic changes in nutrient composition and gene expression during persimmon fruit development. [PDF]

BMC Plant Biol
Yang Y, Duan C, Tian S, Li H.
europepmc   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Multi-objective optimization of germination process parameters of browntop millet (Brachiaria ramosa) grains for improved bioactive compound production using response surface methodology and genetic algorithm approaches. [PDF]

BMC Plant Biol
Kang P, Gurumayum S, Meher SK, Nanda V, Kaur S, Abdi G.   +5 more
europepmc   +1 more source

Helicalization of Covalent Organic Framework Nanofibers with Amplified Spin Polarizability for Boosting Photocatalytic Hydrogen Evolution

Advanced Science, EarlyView.
A non‐covalent chirality‐induced strategy via chiral solvents is presented to synthesize helical 2D COF nanofibers with high crystallinity, high chirality, and high spin polarization. The helical structure enhances the concentration of photogenerated charges, suppresses exciton recombination, and extends carrier lifetimes, thereby significantly ...
Qi Zhong, Yongtu Tian, Yutao Sang, Changchun Wang, Jia Guo   +4 more
wiley   +1 more source

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source

Exogenous 2-Keto-L-Gulonic Acid Supplementation Promotes L-Ascorbic Acid Biosynthesis in Drosophila melanogaster. [PDF]

Int J Mol Sci
Meng C, Xu H.
europepmc   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

Advanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi, Chaoli Chen, Zaohong Ran, Jianning Liao, Zian Wu, Xiaodong Wang, Yongheng Zhao, Wenkai Ke, Bowen Tan, Yun Liu, Youqiang Su, Wei Ren, Xiang Li, Changjiu He   +13 more
wiley   +1 more source

Biochemical and metabolite dynamics during ripening of wood apple (Feronia limonia L.) fruits. [PDF]

BMC Plant Biol
Singh A, Singh A, Gupta AK, Singh A, Damodaran T, Singh NS, Beer K, Ravi SC, Rastogi D, Mishra P.   +9 more
europepmc   +1 more source