Results 1 to 10 of about 165,907 (163)

Determination of the microscopic acid dissociation constant of piperacillin and identification of dissociated molecular forms [PDF]

open access: yesFrontiers in Chemistry, 2023
For amphoteric ß-lactam antibiotics, the acid dissociation constant (pKa) is a fundamental parameter to characterize physicochemical and biochemical properties of antibiotics and to predict persistence and removal of drugs.
Guoao Li   +5 more
doaj   +4 more sources

Applicability of hybrid micelle liquid chromatography for practical determination of acid dissociation constant

open access: yesJournal of Taibah University for Science, 2022
Hybrid micellar liquid chromatography was used for practical determination of acid dissociation constant (pKa) of three analytes, namely, ibuprofen (IBU), naproxen (NPX) and benzoic acid (BZA).
M. E. K. Wahba, D. El Sherbiny
doaj   +2 more sources

The acid dissociation constants of mellitic acid

open access: yesCHIMIA, 1977
The acid dissociation constants of mellitic acid were evaluated at 25 °C from potentiometric titrations in aqueous solutions of the constant Na+ molarity 3 M consisting preponderantly of NaClO4. The obtained values are summarized in the table.
Adrian Beutler, Anton Stebler
doaj   +2 more sources

Favipiravir Determination in Pharmaceutical Formulation via HPLC Chromatographic Approach [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2023
Favipiravir is a broad-spectrum antiviral drug and it has increasing interest regarding its potential use in Covid-19 therapy.  In the present work, a simple, fast, precise Reverse-Phase High-Performance Liquid Chromatography (RP-HPLC) technique was ...
Sabriye Aydinoglu, Metin Bozyel
doaj   +1 more source

SYNTHESIS AND IDENTIFICATION OF SOME HYDROXAMIC DERIVATIVES AND STUDYING THEIR THERMO AND PHOTO DEGRADATION [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة, 2014
The aim of this research is to prepare and study the kinetics effect of temperature and photochemical reactions of the hydroxamic acid derivatives of diethyl succinate through the interaction of alkyl halides and diethyl succinate in the presence of ...
ISMAIL AL-KHATEEB   +2 more
doaj   +1 more source

Determination of the Dissociation Constants of 16 Active Ingredients in Medicinal Herbs Using a Liquid–Liquid Equilibrium Method

open access: yesSeparations, 2021
The dissociation constant is an important physicochemical property of drug molecules that affects the pharmacokinetic and pharmacodynamic properties of drugs.
Wanying Wang   +5 more
doaj   +1 more source

Acid dissociation constants of glycopeptides [PDF]

open access: yesBiochemical Journal, 1977
Glycopeptides containing mainly four amino acid residues in the sequence Asn-Leu-Thr-Ser, with small amounts of additional amino acid residues, were isolated from enzymic hydrolysates of hen's-egg albumin. Heterogeneity of the carbohydrate moiety was confirmed. Acid-base titrations showed that the alpha-amino group has a pKa value of 6.43 at 25 degrees
B M, Austen, R D, Marshall
openaire   +2 more sources

Investigating the impact of chemical structures on the photocatalytic degradation rates over ZnO nanorods: An oxidative pathways perspective

open access: yesCatalysis Communications, 2023
Zinc oxide (ZnO) nanorods were coated on glass substrates and used as photocatalysts to evaluate the kinetic behavior of three different aromatic structures: i) single aromatic ring (phenol), ii) poly-aromatic ring (methylene blue), and iii) complex ...
Elie A. Daher   +3 more
doaj   +1 more source

Modified Stability of microRNA-Loaded Nanoparticles

open access: yesPharmaceutics, 2022
microRNAs represent promising drugs to treat and prevent several diseases, such as diabetes mellitus. microRNA delivery brings many obstacles to overcome, and one strategy to bypass them is the manufacturing of self-assembled microRNA protein ...
Katja Fresacher-Scheiber   +6 more
doaj   +1 more source

Accelerated Evolution of Cytochrome c in Higher Primates, and Regulation of the Reaction between Cytochrome c and Cytochrome Oxidase by Phosphorylation

open access: yesCells, 2022
Cytochrome c (Cc) underwent accelerated evolution from the stem of the anthropoid primates to humans. Of the 11 amino acid changes that occurred from horse Cc to human Cc, five were at Cc residues near the binding site of the Cc:CcO complex. Single-point
Sue Ellen Brand   +10 more
doaj   +1 more source

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