Results 1 to 10 of about 167,504 (265)

Determination of the microscopic acid dissociation constant of piperacillin and identification of dissociated molecular forms [PDF]

Frontiers in Chemistry, 2023
For amphoteric ß-lactam antibiotics, the acid dissociation constant (pKa) is a fundamental parameter to characterize physicochemical and biochemical properties of antibiotics and to predict persistence and removal of drugs.
Guoao Li, Yaling Wang, Yaling Wang, Chengyi Sun, Chengyi Sun, Fei Liu   +5 more
doaj   +2 more sources

Favipiravir Determination in Pharmaceutical Formulation via HPLC Chromatographic Approach [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2023
Favipiravir is a broad-spectrum antiviral drug and it has increasing interest regarding its potential use in Covid-19 therapy.  In the present work, a simple, fast, precise Reverse-Phase High-Performance Liquid Chromatography (RP-HPLC) technique was ...
Sabriye Aydinoglu, Metin Bozyel
doaj   +1 more source

SYNTHESIS AND IDENTIFICATION OF SOME HYDROXAMIC DERIVATIVES AND STUDYING THEIR THERMO AND PHOTO DEGRADATION [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2014
The aim of this research is to prepare and study the kinetics effect of temperature and photochemical reactions of the hydroxamic acid derivatives of diethyl succinate through the interaction of alkyl halides and diethyl succinate in the presence of ...
ISMAIL AL-KHATEEB, SADDA ABEDULLAH, SLMAN AHMED   +2 more
doaj   +1 more source

Determination of the Dissociation Constants of 16 Active Ingredients in Medicinal Herbs Using a Liquid–Liquid Equilibrium Method

Separations, 2021
The dissociation constant is an important physicochemical property of drug molecules that affects the pharmacokinetic and pharmacodynamic properties of drugs.
Wanying Wang, Baixiu Zheng, Jiahao Wu, Weisong Lv, Peiying Lin, Xingchu Gong   +5 more
doaj   +1 more source

Investigating the impact of chemical structures on the photocatalytic degradation rates over ZnO nanorods: An oxidative pathways perspective

Catalysis Communications, 2023
Zinc oxide (ZnO) nanorods were coated on glass substrates and used as photocatalysts to evaluate the kinetic behavior of three different aromatic structures: i) single aromatic ring (phenol), ii) poly-aromatic ring (methylene blue), and iii) complex ...
Elie A. Daher, Cédric Boissière, Christel Laberty Robert, Wael Hamd   +3 more
doaj   +1 more source

Modified Stability of microRNA-Loaded Nanoparticles

Pharmaceutics, 2022
microRNAs represent promising drugs to treat and prevent several diseases, such as diabetes mellitus. microRNA delivery brings many obstacles to overcome, and one strategy to bypass them is the manufacturing of self-assembled microRNA protein ...
Katja Fresacher-Scheiber, Ivana Ruseska, Henrik Siboni, Martin Reiser, Fabio Falsone, Leonhard Grill, Andreas Zimmer   +6 more
doaj   +1 more source

Accelerated Evolution of Cytochrome c in Higher Primates, and Regulation of the Reaction between Cytochrome c and Cytochrome Oxidase by Phosphorylation

Cells, 2022
Cytochrome c (Cc) underwent accelerated evolution from the stem of the anthropoid primates to humans. Of the 11 amino acid changes that occurred from horse Cc to human Cc, five were at Cc residues near the binding site of the Cc:CcO complex. Single-point
Sue Ellen Brand, Martha Scharlau, Lois Geren, Marissa Hendrix, Clayre Parson, Tyler Elmendorf, Earl Neel, Kaila Pianalto, Jennifer Silva-Nash, Bill Durham, Francis Millett   +10 more
doaj   +1 more source

Applicability of hybrid micelle liquid chromatography for practical determination of acid dissociation constant

Journal of Taibah University for Science, 2022
Hybrid micellar liquid chromatography was used for practical determination of acid dissociation constant (pKa) of three analytes, namely, ibuprofen (IBU), naproxen (NPX) and benzoic acid (BZA).
M. E. K. Wahba, D. El Sherbiny
doaj   +1 more source

Student exploration of the Henderson-Hasselbach equation and pH readings to determine the pK a value of 4,4′-trimethylenedipiperidine (TMDP)

Chemistry Teacher International, 2023
This educatory experiment uses an inexpensive pH meter to determine an approximate negative logarithm of the acid dissociation constant (pK a) value of 4,4′-trimethylenedipiperidine (TMDP).
Zaharani Lia, Khaligh Nader Ghaffari
doaj   +1 more source

Adsorption of itaconic acid from aqueous solutions onto alumina [PDF]

Journal of the Serbian Chemical Society, 2008
Itaconic acid, IA (C5H6O4), was investigated as a potential flocculant for the aqueous processing of alumina powders. The adsorption of IA, as a function of its concentration and pH value of the solution, onto the alumina surface was studied by the ...
Gulicovski Jelena J., Čerović Ljiljana S., Milonjić Slobodan K., Popović Ivanka G.   +3 more
doaj   +3 more sources