Results 41 to 50 of about 799,475 (353)

Acid Hydrolysis of Urinary Estriol

open access: yesClinical Chemistry, 1967
Abstract One hundred and twenty determinations of urinary estriol were carried out following acid hydrolysis and gas liquid chromatography. Through the use of a radioactive standard, it was shown that, with an increase in specific gravity (1.001 to 1.025), a steady linear decline of estriol recovery occurred (93% to 56%). The presence of
A E, Schindler   +2 more
openaire   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Profiles of Free and Bound Phenolics and Their Antioxidant Capacity in Rice Bean (Vigna umbellata)

open access: yesFoods, 2023
Rice bean (Vigna umbellata) is a medicinal and dietary legume rich in polyphenols. In this study, the free and bound phenolics in rice bean were extracted by water, 80% methanol, and acid, base, and composite enzymatic hydrolysis, respectively.
Qinzhang Jiang   +5 more
doaj   +1 more source

Glucose Content of Sago Waste After Chloride Acid Pre- Treatment Hydrolysis For Bioethanol Production [PDF]

open access: yes, 2015
Indonesia is a country with abundant agricultural biological resources. One of the plants as a biological source is sago. Sago processing wastes such as bark and waste about 72%.
A, Agustina LN   +6 more
core  

Hydrolysis of digoxin by acid

open access: yesJournal of Pharmacy and Pharmacology, 1977
AbstractPredictable hydrolysis of [3H]digoxin-12α occurred in vitro with incubation in HCl or gastric juice. Hydrolysis varied with pH, time, temperature and agitation. Digoxin, the bis- and mono-digitoxosides of digoxigenin and digoxigenin were separated by silica gel thin-layer chromatography using chloroform-ethyl acetate-glacial acetic acid (25:25 ...
M H, Gault   +3 more
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Microwave-mediated analysis for sugar, fatty acid, and sphingoid compositions of glycosphingolipids

open access: yesJournal of Lipid Research, 2004
For chemical characterization of glycosphingolipids, it is necessary to determine the chemical compositions of three constituents, i.e., sugars, fatty acids, and sphingoids.
Saki Itonori   +5 more
doaj   +1 more source

Nerve Agent Hydrolysis Activity Designed into a Human Drug Metabolism Enzyme [PDF]

open access: yes, 2010
Organophosphorus (OP) nerve agents are potent suicide inhibitors of the essential neurotransmitter-regulating enzyme acetylcholinesterase. Due to their acute toxicity, there is significant interest in developing effective countermeasures to OP ...
Andrew C. Hemmert   +15 more
core   +6 more sources

Enzymic Hydrolysis of Colanic Acid [PDF]

open access: yesEuropean Journal of Biochemistry, 1971
The isolation of of oligosaccharides produced by the action of phage-inducee enzymes on the bacterial exopolysaccharide colanic acid is reported. The products from colanic acid produced by different strains of Escherichia coli and Salmonella typhimurium were hexasaccharides which differed in their acyl substituents.
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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