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Targeting Acid-Sensing Ion Channels in Disease
Acidosis is a central feature of many pathological conditions, and while the activity of many ion channels is suppressed under acidic conditions, acid-sensing ion channels (ASICs) are exquisitely sensitive to decreases in pH and activated by protons. The expression and function of ASICs is enhanced under conditions of ischemia, inflammation, and trauma.Senescall, Victor +9 more
openaire +3 more sources
Acidāsensing ion channels in allergic rhinitis
Clinical & Experimental Allergy, 2012openaire +3 more sources
Acid-sensing Ion Channels: Implications for Intervertebral Disc Degeneration
Current Pharmaceutical Biotechnology, 2023Rui Ran
exaly
Acid-sensing ion channels in healthy and degenerated human intervertebral disc
Connective Tissue Research, 2014Roberto Cabo +2 more
exaly
Acid-sensing ion channels: Linking extracellular acidification with atherosclerosis
Clinica Chimica Acta, 2020Hong-Feng Gu
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