Results 71 to 80 of about 2,612,325 (310)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Oxidative Changes of Lipids during Microwave Heating of Minced Fish Flesh in Catering

open access: yesCzech Journal of Food Sciences, 2009
The influence of microwave heating (microwave oven Electrolux, 2450 MHz, 400 W) from 8 up to 24 min on the oxidation and fatty acid composition of lipids of common carp (Cyprinus carpio) and Atlantic mackerel (Scomber scombrus) minced fish flesh were ...
E. Abd El-Moneim Mahmoud   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Adipic acid : MAK Value Documentation, 2017 [PDF]

open access: yes, 2018
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has evaluated adipic acid [124‐04‐9] to derive a maximum concentration at the workplace (MAK value), considering all toxicity endpoints.
Hartwig, Andrea   +2 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Effects of Extraction Process Parameters on the Quality Characteristics of Parinari Polyandra B. Seed Oil

open access: yesNigerian Journal of Technological Development, 2016
Extraction process parameters can influence the quality of oil obtained from seeds during extraction process. The effect of extraction process parameters on the quality of parinari seed oil, a potential renewable industrial raw material, is yet to be ...
T. E. Odetoye   +2 more
doaj  

Fermentative Itaconic Acid Production [PDF]

open access: yes, 2014
Itaconic acid is an organic acid that is used as a platform chemical for the production of various value added chemicals such as poly-itaconic acid, resins biofuel components, ionomer cements etc.
El-Imam, Ahmed A., Du, Chenyu
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

AMINO ACID DIGESTIBILITIES OF PALM KERNEL MEAL IN POULTRY [PDF]

open access: yes, 2008
Palm kernel meal (PKM) is produced in large quantities in many parts of the world. Problems associated with PKM are due to their high fibre content, imbalanced amino acid ratios, the possibility of Maillard products and their own physical ...
Kumar, A, Dingle, J, Sundu, B
core  

Methoxyacetic acid – Evaluation of a BAT value [PDF]

open access: yes
The German Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area (MAK Commission) summarized and evaluated the data for methoxyacetic acid [625-45-6] to derive a biological tolerance value (BAT value ...
Hartwig, Andrea; https://orcid.org/   +4 more
core   +1 more source

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