Results 41 to 50 of about 327,594 (295)
Responses of Free-Living Planktonic Bacterial Communities to Experimental Acidification and Warming
Microorganisms, 2023 Climate change driven by human activities encompasses the increase in atmospheric CO2 concentration and sea-surface temperature. Little is known regarding the synergistic effects of these phenomena on bacterial communities in oligotrophic marine ...
Anastasia Tsiola +6 more
doaj +1 more source
Exposure to low pH induces molecular level changes in the marine worm, Platynereis dumerilii [PDF]
, 2015 © 2015 Elsevier Inc. Fossil fuel emissions and changes in net land use lead to an increase in atmospheric CO 2 concentration and a subsequent decrease of ocean pH. Noticeable effects on organisms' calcification rate, shell structure and energy metabolism
Hardege, Jörg D. +3 more
core +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Lysosomal Acidification Mechanisms [PDF]
Annual Review of Physiology, 2012 Lysosomes, the terminal organelles on the endocytic pathway, digest macromolecules and make their components available to the cell as nutrients. Hydrolytic enzymes specific to a wide range of targets reside within the lysosome; these enzymes are activated by the highly acidic pH (between 4.5 and 5.0) in the organelles' interior. Lysosomes generate and
openaire +2 more sources
Short-term effects of CO₂-induced low pH exposure on target gene expression in Platynereis dumerilii [PDF]
, 2016 Objective: Increasing atmospheric CO₂ concentration are causing changes to the seawater carbonate chemistry, lowering the pH and we study potential impacts of these changes at the molecular level in a non-calcifying, marine polychaete species Platynereis
Hardege, Jorg D +4 more
core +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Evidence of Springwater Acidification in the Vosges Mountains (North-East of France): Influence of Bedrock Buffering Capacity [PDF]
, 1999 Investigations on springwater acidity were carried out in the Vosges mountains (north-eastern France). Acid or poorly buffered spring and streamwaters were detected in the same area.
Dambrine, Etienne +5 more
core +2 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Recovery of Streams in the Harz National Park (Germany)—The Attenuation of Acidification
EcologiesBetween 1995 and 2022, 19 measuring points in small and medium sized streams in the Harz National Park, Germany, were sampled. The samples were evaluated in terms of their macroinvertebrate (MI) biology and hydrochemistry.
Uta Langheinrich +4 more
doaj +1 more source
Community-level response of coastal microbial biofilms to ocean acidification in a natural carbon dioxide vent ecosystem. [PDF]
, 2012 The version on PEARL: Corrected proofs are Articles in Press that contain the authors' corrections. Final citation details, e.g., volume/issue number, publication year and page numbers, still need to be added and the text might change before final ...
Cunliffe, M +4 more
core +2 more sources