Results 51 to 60 of about 324,577 (276)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Reproductive Response of Platynothrus peltifer (C.L. Koch, 1839) to Continuous Nitrogen Deposition

Diversity
Continuous nitrogen deposition threatens ecosystems by acidifying soils, causing a stoichiometric imbalance in the vegetation and ultimately, the disappearance of plant and animal species.
Marie-Charlott Petersdorf, Joren Bruggink, Evy A. de Nijs, Henk Siepel   +3 more
doaj   +1 more source

NAD-Glycohydrolase Depletes Intracellular NAD+ and Inhibits Acidification of Autophagosomes to Enhance Multiplication of Group A Streptococcus in Endothelial Cells

Frontiers in Microbiology, 2018
Group A Streptococcus (GAS) is a human pathogen causing a wide spectrum of diseases, from mild pharyngitis to life-threatening necrotizing fasciitis. GAS has been shown to evade host immune killing by invading host cells.
Cheng-Lu Hsieh, Hsuan-Min Huang, Shu-Ying Hsieh, Po-Xing Zheng, Yee-Shin Lin, Yee-Shin Lin, Chuan Chiang-Ni, Chuan Chiang-Ni, Pei-Jane Tsai, Shu-Ying Wang, Ching-Chuan Liu, Ching-Chuan Liu, Jiunn-Jong Wu, Jiunn-Jong Wu   +13 more
doaj   +1 more source

Early Diagenesis in the Hypoxic and Acidified Zone of the Northern Gulf of Mexico: Is Organic Matter Recycling in Sediments Disconnected From the Water Column?

Frontiers in Marine Science, 2021
Hypoxia and associated acidification are growing concerns for ecosystems and biogeochemical cycles in the coastal zone. The northern Gulf of Mexico (nGoM) has experienced large seasonal hypoxia for decades linked to the eutrophication of the continental ...
Christophe Rabouille, Bruno Lansard, Shannon M. Owings, Nancy N. Rabalais, Bruno Bombled, Edouard Metzger, Julien Richirt, Eryn M. Eitel, Anthony D. Boever, Jordon S. Beckler, Martial Taillefert   +10 more
doaj   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Impact of ocean acidification on microzooplankton grazing dynamics

Frontiers in Marine Science
This study examines the potential impacts of projected atmospheric carbon dioxide (pCO2) levels reaching 800 ppm by the end of the century, focusing on ocean acidification effects on marine ecosystems in the coastal areas of Bohai.
Wenting Shi, Wenting Shi, Wenting Shi, Xiaoting Fu, Xiaoting Fu, Xiaoting Fu, Yabo Han, Yabo Han, Yabo Han, Jiahui Qin, Jiahui Qin, Jiahui Qin, Jun Sun, Jun Sun, Jun Sun   +14 more
doaj   +1 more source

Changes in Eutric Cambisol due to long-term mineral fertilisation: A case study in Serbia

Italian Journal of Agronomy, 2022
The paper presents the results of a 50-year fertilisation experiment on Eutric Cambisol with increasing doses of nitrogen and constant doses of phosphorus and potassium.
Nikola Koković, Goran Jačimović, Biljana Sikirić, Vladimir Čirić, Vladan Ugrenović, Aigul Zhapparova, Elmira Saljnikov   +6 more
doaj   +1 more source

USING VOLCANIC MARINE CO2 VENTS TO STUDY THE EFFECTS OF OCEAN ACIDIFICATION ON BENTHIC BIOTA: HIGHLIGHTS FROM CASTELLO ARAGONESE D’ISCHIA (TYRRHENIAN SEA) [PDF]

, 2010
Current research into ocean acidification is mainly being carried out using short-term experiments whereby CO2 levels are manipulated in aquaria and enclosures.
Buia, MC, Cigliano, M, Cocito, S, Gambi, MC, Hall-Spencer, JM, Lombardi, C, Lorenti, M, Patti, FP, Porzio, L, Rodolfo-Metalpa, R, Scipione, MC   +10 more
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Study of the Acidification of Sherry Musts With Gypsum and Tartaric Acid [PDF]

, 1993
Must acidification is a necessary operation in hot regions due to the low natural acid content of the grapes grown there. Tartaric acid is what is most usually used for this purpose.
Diez Martín, Juan, Grandal Delgado, María del Mar, Gómez Benítez, Juan   +2 more
core   +1 more source