Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Artificial intelligence as a tool to study the 3D skeletal architec-ture in newly settled coral recruits: insights into the effects of Ocean Acidification on coral biomineralization [PDF]
, 2022 Federica Scucchia +3 more
openalex +1 more source
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Modulation of iron responsive gene expression and enzymatic activities in response to changes of the iron nutritional status in _Cucumis sativus_ L. [PDF]
, 2010 Regulation exerted by the iron status of the plant on the iron deficiency responses was investigated in cucumber roots (_Cucumis sativus_ L.) both at the biochemical and molecular level. Absence of iron induced the expression of the CsFRO1, CsIRT1, CsHA1
Gianpiero Vigani +2 more
core +2 more sources
Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew +11 more
wiley +1 more source
Histidine Protonation and Conformational Switching in Diphtheria Toxin Translocation Domain
Toxins, 2023 Protonation of key histidine residues has been long implicated in the acid-mediated cellular action of the diphtheria toxin translocation (T-) domain, responsible for the delivery of the catalytic domain into the cell.
Mykola V. Rodnin +9 more
doaj +1 more source
Short-term effects of CO₂-induced low pH exposure on target gene expression in Platynereis dumerilii [PDF]
, 2016 Objective: Increasing atmospheric CO₂ concentration are causing changes to the seawater carbonate chemistry, lowering the pH and we study potential impacts of these changes at the molecular level in a non-calcifying, marine polychaete species Platynereis
Hardege, Jorg D +4 more
core +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
, 2014 Acidification is caused by emissions of sulphur dioxide (SO2), nitrogen oxides (NOx), and ammonia (NH3), of which sulphur emissions are the primary source. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789 ...
+5 more sources
Key Scientific Developments Since the IPCC Fourth Assessment Report [PDF]
, 2009 Provides an overview of peer-reviewed research published between July 2006 and June 2009 on fossil fuel emissions; ocean acidification; projected sea level rises; rates of ice and permafrost melting and thawing, and the lasting impacts of global ...
core