Results 101 to 110 of about 202,074 (311)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Effect of ultrasonic and infrared treatments on microbial population, physicochemical properties, and total phenols of sprouted wheat powder [PDF]
فناوریهای جدید در صنعت غذاSprouting is a simple technique for improving the nutritional and quality characteristics of cereal grains. The purpose of this work was to examine ultrasonic pretreatment and drying methods (hot-air and infrared) on microbial population (total bacterial
samira Amin-Ekhlas +2 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Shapeshifting Ligands Mask Lewis Acidity of Dicationic Palladium(II)
Supporting ligands limit the degree of electrophilic ac-tivation for any substrate because they also reduce the Lewis acidity of the transition metal ion.
Jonathan, Kuo +3 more
core +1 more source
, 2019 The development of an intelligent biomaterial system that can efficiently accumulate at the tumor site and release a drug in a controlled way is very important for cancer chemotherapy.
Ru Bai +17 more
core +1 more source
Quality of drinking water from the agricultural area treated with pitcher water filters
Roczniki Panstwowego Zakladu Higieny, 2018 Background. Home methods of drinking water treatment through filtration have recently become quite popular. Objective. The aim of the study was to compare chemical composition of unfiltered water with water filtered in households with pitcher water ...
Elżbieta Królak +3 more
doaj
INFLUENCE OF CHEMICAL FERTILIZATION ON STRAWBERRY FRUIT PROPERTIES [PDF]
Fruit Growing Research, 2012 The worldwide trend of plantations fertilization imposed a new concept in this field. On one hand, it was abandoned the idea of using large amounts of fertilizer to force the obtaining of high yields, and on the other hand, increasingly require more and ...
Alina Florea, Alexandru Teodorescu
doaj
THE HOMOGENIZED VEGETABLE PASTES AND MARINADES WITH BERRY COMPONENTA
Современная наука и инновации, 2022 In article possibility of use of a residue of berries of cowberry and a cranberry is studied for production of the homogenized pastes and marinades with a residue of berries of cowberry and a cranberry ofthe increased microbiological firmness.
Galina Valentinovna Ivanova +1 more
doaj
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source