Results 111 to 120 of about 413,131 (263)
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Determination of individual sugars and organic acids of New Zealand varietal apple juice and their use in evaluating authenticity : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Food Technology at Massey University [PDF]
High pressure liquid chromatography techniques were used to determine sugars and acids in the juice of apples grown in New Zealand. A total of 189 samples were analysed and the results were used to assist with the determination of the authenticity of New
Radford, Garry Charles
core
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Limnology of Four Bauxite Open-Pit Lakes [PDF]
The aquatic flora and fauna and 18 physicochemical characteristics of four bauxite open-pit lakes were studied from September 1969 to August 1970. The least acid lake (pH 3.4-4.4) supported 49 different aquatic insects, plankton, and higher aquatic ...
Harp, George L., Hubbard, Ronald D.
core +2 more sources
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Pinot Gris: Oregon’s Signature White Wine [PDF]
Rusty Gaffney writes about Oregon\u27s Pinot Gris in a question-and-answer session with several Willamette Valley winemakers in this article from his Prince of Pinot blog, volume 7, issue 15.
Gaffney, William Rusty
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Examining the PM6 semiempirical method for pKa prediction across a wide range of oxyacids [PDF]
The pK~a~ estimation ability of the semiempirical PM6 method was evaluated across a broad range of oxyacids and compared to results obtained using the SPARC software program.
Kaya Forest +2 more
core +1 more source

