Results 51 to 60 of about 202,074 (311)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Acidity-Activated Charge-Convertible Silver Nanocomposites for Enhanced Bacteria-Specific Aggregation and Antibacterial Activity

, 2019
Bacterial infections has become an intractable problem to human health. To overcome this challenge, we developed an antimicrobial agent (AgNPs@PDPE) via the conjugation of a pH-responsive copolymer of PDMAEMA-b-PPEGMA onto AgNPs surface.
Guoping Wu, Qianqian Guo (339283), Guoping Wu (1329075), Yi Chen, Zhaoxiong Ma (6953240), Zhaoxiong Ma, Yini Xu, Mingsong Liao (6953243), Mingsong Liao, Tianyu Lan (5139758), Xiangchun Shen, Tianyu Lan, Ting Xiao (38895), Yi Chen (38576), Xiangchun Shen (4614574), Ting Xiao, Yini Xu (3512828), Qianqian Guo   +17 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Influence of the Invasive Species Ailanthus altissima (Tree of Heaven) on Yield Performance and Olive Oil Quality Parameters of Young Olive Trees cv. Koroneiki Under Two Distinct Irrigation Regimes

Applied Sciences
Ailanthus altissima (AA) is an invasive tree species rapidly spreading worldwide, colonizing both urban and agricultural or forestry environments. This three-year study aimed to assess its effects on the growth and yield traits of the Koroneiki olive ...
Asimina-Georgia Karyda, Petros Anargyrou Roussos   +1 more
doaj   +1 more source

Calagem superficial e cobertura de aveia preta antecedendo os cultivos de milho e soja em sistema plantio direto Surface lime application and black oat cover preceding corn and soybean crops under a no-till system

Revista Brasileira de Ciência do Solo, 2006
Os resíduos de plantas de cobertura podem mobilizar cátions no solo e beneficiar a ação da calagem superficial, por meio da liberação de ácidos orgânicos de baixo peso molecular da fração solúvel dos resíduos.
Eduardo Fávero Caires, Fernando José Garbuio, Luís Reynaldo Ferracciú Alleoni, Michel Alexandro Cambri   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

109Ag NMR Chemical Shift as a Descriptor for Brønsted Acidity from Molecules to Materials

, 2023
Molecular-level understanding of the acid/base properties of heterogeneous catalysts requires the development of selective spectroscopic probes to establish structure-activity relationships.
Scott R., Docherty, Alexander V., Yakimov, Christophe, Copéret, Colin, Hansen, Weicheng, Cao   +4 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Selenium Speciation in the Fountain Creek Watershed (Colorado, USA) Correlates with Water Hardness, Ca and Mg Levels

Molecules, 2017
The environmental levels of selenium (Se) are regulated and strictly enforced by the Environmental Protection Agency (EPA) because of the toxicity that Se can exert at high levels. However, speciation plays an important role in the overall toxicity of Se,
James S. Carsella, Irma Sánchez-Lombardo, Sandra J. Bonetti, Debbie C. Crans   +3 more
doaj   +1 more source