Results 41 to 50 of about 235,106 (262)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Acidic Mesoporous Zeolite ZSM-5 Supported Cu Catalyst with Good Catalytic Performance in the Hydroxysulfurization of Styrenes with Disulfides

open access: yesNanomaterials, 2017
Development of highly active heterogeneous catalysts is an effective strategy for modern organic synthesis chemistry. In this work, acidic mesoporous zeolite ZSM-5 (HZSM-5-M), acidic-free mesoporous zeolite TS-1 (TS-1-M), and basic ETS-10 zeolite ...
Jun Hu   +9 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Efficient Lewis Acid Ionic Liquid-Catalyzed Synthesis of the Key Intermediate of Coenzyme Q10 under Microwave Irradiation

open access: yesMolecules, 2010
An efficient synthesis of a valuable intermediate of coenzyme Q10 by microwave-assisted Lewis acidic ionic liquid (IL)-catalyzed Friedel-Crafts alkylation is reported.
Thomas Efferth   +6 more
doaj   +1 more source

Zeolite deactivation during hydrocarbon reactions: characterisation of coke precursors and acidity, product distribution [PDF]

open access: yes, 2008
The catalytic conversion of hydrocarbons over zeolites has been applied in large scale petroleum-refining processes. However, there is always formation and retention of heavy by-products, called coke, which causes catalyst deactivation. This deactivation
Wang, B.
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Calagem superficial e cobertura de aveia preta antecedendo os cultivos de milho e soja em sistema plantio direto Surface lime application and black oat cover preceding corn and soybean crops under a no-till system

open access: yesRevista Brasileira de Ciência do Solo, 2006
Os resíduos de plantas de cobertura podem mobilizar cátions no solo e beneficiar a ação da calagem superficial, por meio da liberação de ácidos orgânicos de baixo peso molecular da fração solúvel dos resíduos.
Eduardo Fávero Caires   +3 more
doaj   +1 more source

Is Lewis Acidity in Metal Dications Triggered by Solvent Shell Fluctuations? [PDF]

open access: yes, 2018
Using experimental data collected on the stabilities of gas phase clusters consisting of metal dications in association with water molecules, a model is proposed to account for Lewis acidity.
Tony Stace   +2 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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