Results 111 to 120 of about 395,864 (260)
Factor equivalence of Galois modules and regulator constants [PDF]
, 2013 We compare two approaches to the study of Galois module structures: on the one hand, factor equivalence, a technique that has been used by Fröhlich and others to investigate the Galois module structure of rings of integers of number fields and of their ...
Bartel, Alex, Alex Bartel
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Horticultural Plant JournalCitric acid is an important contributor to fruit flavor. The extremely significant differences in citric acid levels are observed among citrus species and varieties.
Jiaxian He +7 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Regulator engagement with small business [PDF]
, 2013 This draft report was released to assist participants in preparing a submission to the commissioned study into Regulator Engagement with Small Business. Members of the public are invited to examine this draft and provide written comment.
Productivity Commission
core
Nature CommunicationsCovering 40–50% of world’s arable lands, acidic soils pose a major constraint on global crop productivity by severely restricting root development and nutrient acquisition.
Jia Yuan Ye +11 more
doaj +1 more source
Engineered SciencePhosphogypsum (PG) is a bulk solid waste characterized by high acidity and toxic elements, causing environmental pollution risks. This study proposes a targeted solidification/stabilization (S/S) method using quicklime as an alkaline regulator and ...
Yiting Wang +4 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source