Results 91 to 100 of about 9,968 (290)
Synthetic auxins, specially 2,4-dichlorophenoxyacetic acid (2,4-D), have been used as a postharvest treatment to retard calyx abscission, drying and browning, which occur as the result of degreening processes. Nevertheless, the use of 2,4-D is restricted
Navarro, Pilar +2 more
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
The kidney and acid-base regulation
Since the topic of the role of the kidneys in the regulation of acid-base balance was last reviewed from a teaching perspective (Koeppen BM. Renal regulation of acid-base balance. Adv Physiol Educ 20: 132–141, 1998), our understanding of the specific membrane transporters involved in H+, HCO3−, and NH4+ transport, and especially how these transporters
openaire +2 more sources
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Engineered global regulator H-NS improves the acid tolerance of E. coli
Background Acid stress is often encountered during industrial fermentation as a result of the accumulation of acidic metabolites. Acid stress increases the intracellular acidity and can cause DNA damage and denaturation of essential enzymes, thus leading
Xiaofeng Yang +5 more
core +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Model of ExoR-ChvG/ChvI-induced T6SS activation via acidity.
(A) In neutral pH, ExoR associates with transmembrane sensor kinase ChvG and represses the ChvG/ChvI two-component system signaling, thus leading to reduced T6SS expression and secretion activity.
Chih-Feng Wu (117145) +3 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
A coloração e o tamanho são fatores determinantes na qualidade dos frutos de caroço. Por este motivo, foram utilizadas duas práticas culturais, anelamento de ramos e aplicação de regulador vegetal, com o objetivo de melhorar a qualidade de frutos de ...
Milene Ronconi Vieira +1 more
core +1 more source
High rainfall and low temperatures can cause grapes not to reach adequate maturation indexes. The aim of this work was to evaluate the effect of leaf removal, hormonal regulator and vegetable extracts on the quality of grape and wine.
Isabela Leticia Pessenti +2 more
doaj +1 more source

