Results 71 to 80 of about 430,684 (299)

Interfacial Acidity on Oxide Surfaces: A Scaling Paradigm and the Role of the Hydrogen Bond [PDF]

open access: yes, 2020
A fundamental understanding of acidity at an interface, as mediated by structure and molecule-surface interactions, is essential to elucidate the mechanisms of a range of chemical transformations. While the strength­­­­ of an acid in the gas and solution
Robert, Chapleski   +11 more
core   +3 more sources

Regulation of mTOR by Phosphatidic Acid? [PDF]

open access: yesCancer Research, 2007
Abstract Interest in the regulation of the mammalian target of rapamycin (mTOR) has increased substantially in recent years largely because of an apparent link between mTOR and survival signals in human cancer cells. Much has been learned about the regulation of mTOR in response to survival signals generated by phosphatidylinositol 3 ...
openaire   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Efficiency Improvement of LDO Output Based Linear Regulator With Supercapacitor Energy Recovery – A versatile new technique with an example of a 5V to 1.5V version [PDF]

open access: yes, 2011
Supercapacitors are used in various industrial applications and the supercapacitors technology is gradually progressing into a mature state. Common applications of supercapacitors are in electric vehicles, hybrid electric vehicles, uninterruptible power ...
Saiful Riza, Zainul Abidin   +1 more
core  

Effect of zinc oxide nanoparticles synthesis precursor in hydrothermal method on structure and physical properties of poplar wood [PDF]

open access: yesتحقیقات علوم چوب و کاغذ ایران, 2015
In this research, effect of the alkaline precursors of soda and ammonia as reagent deposition of zinc oxide nanoparticles using hydrothermal method in structure and physical properties of poplar wood were investigated.
Elham Hatamzadeh   +2 more
doaj   +1 more source

Regulating uric acid

open access: yeseLife
Certain strains of a bacterium found in the gut of some animals, Lactobacillus plantarum , are able to counter hyperuricemia, a condition caused by high levels of uric acid in the blood.
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

ASIC1 and ASIC3 contribute to acidity-induced EMT of pancreatic cancer through activating Ca2+/RhoA pathway

open access: yes, 2017
Extracellular acid can have important effects on cancer cells. Acid-sensing ion channels (ASICs), which emerged as key receptors for extracellular acidic pH, are differently expressed during various diseases and have been implicated in underlying ...
Shi-Chang Deng   +11 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Gambling Regulator to be Introduced by Autumn.

open access: yes, 2021
The government intends to have a gambling regulator in operation by the Autumn, with the post to be advertised over the coming summer. ..
Gilmore, Mike
core  

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