Results 61 to 70 of about 28,487 (304)

RIP1 Mediates Manzamine-A-Induced Secretory Autophagy in Breast Cancer

Marine Drugs, 2023
Cancer-derived small extracellular vesicles (sEVs) serve as critical mediators of cell-to-cell communication. Manzamine A (MA), a unique marine-derived alkaloid with various bioactivities, exerts anticancer effects against several kinds of tumors, but it
Xuan Wang, Yuanpeng Liu, Huan Qin, Guocui Qi, Xuehong Chen, Yi Lyu, Yantao Han   +6 more
doaj   +1 more source

Bile acids as metabolic regulators [PDF]

Current Opinion in Gastroenterology, 2015
This review focuses on the latest understanding of the molecular mechanisms underlying the complex interactions between intestine and liver bile acid signaling, gut microbiota, and their impact on whole-body lipid, glucose and energy metabolism.Hepatic bile acid synthesis is tightly regulated by the bile acid negative feedback mechanisms.
Tiangang, Li, John Y L, Chiang
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Acid-induced type VI secretion system is regulated by ExoR-ChvG/ChvI signaling cascade in Agrobacterium tumefaciens. [PDF]

PLoS Pathogens, 2012
The type VI secretion system (T6SS) is a widespread, versatile protein secretion system in pathogenic Proteobacteria. Several T6SSs are tightly regulated by various regulatory systems at multiple levels.
Chih-Feng Wu, Jer-Sheng Lin, Gwo-Chyuan Shaw, Erh-Min Lai   +3 more
doaj   +1 more source

Genes commonly involved in acid tolerance are not overexpressed in the plant microsymbiont Mesorhizobium loti MAFF303099 upon acidic shock [PDF]

, 2014
Rhizobia are legume bacterial symbionts that fix nitrogen in the root nodules of plants. The aim of the present study was to investigate the global transcriptional response of rhizobia upon an acidic shock.
Alexandre, Ana, Laranjo, Marta, Oliveira, Solange   +2 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Safety and efficacy of a feed additive consisting of sodium bisulphate for all animal species except aquatic animals (Grillo Werke AG & Jones‐Hamilton Co.)

EFSA Journal
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for renewal of authorisation of sodium bisulphate (SBS) as a feed additive for all terrestrial animal species (category:
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Roberto Edoardo Villa, Ruud Woutersen, Jaume Galobart, Orsolya Holczknecht, Matteo Lorenzo Innocenti, Paola Manini, Anita Radovnikovic, Fabiola Pizzo, Maria Vittoria Vettori, Angelica Amaduzzi   +24 more
doaj   +1 more source

Gibberellic acid in the ‘Cabernet Sauvignon’ grape: effects on grape cluster morphology and wine quality

Revista de Ciências Agroveterinárias, 2023
‘Cabernet Sauvignon’ is a commonly produced and consumed variety of grapes in Brazil, although late sprouting and flowering negatively affect wine production, hindering the production of elegant and balanced wines, especially in high-altitude regions of
Gabriela Zocche Pless , Thiago Moreira Monteiro, Giovani Furini, Milena de Souza Tomaz , Leonam Macedo da Torre , Carolina Pretto Panceri , Rogerio Anese   +6 more
doaj   +1 more source

Investigation of the Influence of Antimicrobial Preparations on the Shelf Life of Broccoli Cabbage [PDF]

, 2018
Studies of the effect of antimicrobial agents on the conservation of broccoli cabbage have been conducted. The late hybrids of broccoli Ironman F1, Agassi F1, Beaumont F1, grown under the conditions of the Forest-Steppe of Ukraine were studied.
Bondarenko, V. (Veronika), Gaevaya, L. (Ludmila), Lyubymova, N. (Nina), Pusik, L. (Ludmila), Pusik, V. (Vlаdimir)   +4 more
core   +2 more sources

Bile acids: regulation of apoptosis by ursodeoxycholic acid [PDF]

Journal of Lipid Research, 2009
Bile acids are a group of molecular species of acidic steroids with peculiar physical-chemical and biological characteristics. At high concentrations they become toxic to mammalian cells, and their presence is pertinent in the pathogenesis of several liver diseases and colon cancer.
Joana D. Amaral, Ricardo J.S. Viana, Rita M. Ramalho, Clifford J. Steer, Cecília M.P. Rodrigues   +4 more
openaire   +3 more sources