Results 41 to 50 of about 9,968 (290)

ASIC1 and ASIC3 contribute to acidity-induced EMT of pancreatic cancer through activating Ca2+/RhoA pathway

open access: yes, 2017
Extracellular acid can have important effects on cancer cells. Acid-sensing ion channels (ASICs), which emerged as key receptors for extracellular acidic pH, are differently expressed during various diseases and have been implicated in underlying ...
Shi-Chang Deng   +11 more
core   +1 more source

Bile acids as metabolic regulators [PDF]

open access: yesCurrent Opinion in Gastroenterology, 2015
This review focuses on the latest understanding of the molecular mechanisms underlying the complex interactions between intestine and liver bile acid signaling, gut microbiota, and their impact on whole-body lipid, glucose and energy metabolism.Hepatic bile acid synthesis is tightly regulated by the bile acid negative feedback mechanisms.
Tiangang, Li, John Y L, Chiang
openaire   +2 more sources

An Investigation of Mn−Ce−Based Conversion Coating on LZ91 Magnesium Alloy

open access: yesInternational Journal of Electrochemical Science, 2018
Most of the magnesium alloys are relatively reactive and tend to suffer corrosion. Consequently, surface modifications are performed to enhance the corrosion resistance and paint adhesion of the base magnesium alloys.
Shun-Yi Jian, Ko-Lun Chang
doaj   +1 more source

Regulation of Abscisic Acid Biosynthesis [PDF]

open access: yesPlant Physiology, 2003
Plant growth and development are regulated by internal signals and by external environmental conditions. One important regulator that coordinates growth and development with responses to the environment is the sesquiterpenoid hormone abscisic acid (ABA).
Liming, Xiong, Jian-Kang, Zhu
openaire   +2 more sources

Responsiveness to acidity via metal ion regulators mediates virulence in the gastric pathogen Helicobacter pylori.

open access: yes, 2004
International audienceThe virulence of pathogenic bacteria is dependent on their adaptation to and survival in the stressful conditions encountered in their hosts. Helicobacter pylori exclusively colonizes the acid stomach of primates, making it an ideal
de Reuse, Hilde   +11 more
core   +1 more source

Environmental regulation of Yersinia pathophysiology

open access: yesFrontiers in Cellular and Infection Microbiology, 2016
Hallmarks of Yersinia pathogenesis include the ability to form biofilms on surfaces, the ability to establish close contact with eukaryotic target cells and the ability to hijack eukaryotic cell signaling and take over control of strategic cellular ...
Shiyun eChen   +2 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Synthesis of aluminium phosphates by chemical precipitation in aqueous solutions varying acidity and component mole ratio

open access: yes, 2021
Food additive E541 is a chemically pure aluminum phosphate, which is used as an emulsifier, stabilizer, leavening agent, acidity regulator, etc. Most often, this food additive is used in confectionery and for baking, because aluminophosphate reacts with ...
Dubenko , A. V.   +2 more
core  

Mother-daughter asymmetry of pH underlies aging and rejuvenation in yeast

open access: yeseLife, 2014
Replicative aging in yeast is asymmetric–mother cells age but their daughter cells are rejuvenated. Here we identify an asymmetry in pH between mother and daughter cells that underlies aging and rejuvenation. Cytosolic pH increases in aging mother cells,
Kiersten A Henderson   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

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