Results 231 to 240 of about 28,487 (304)

A Comparison of the Physicochemical Properties and Sensory Attributes of Ricotta Cheeses Purchased from Retail Outlets in Poland. [PDF]

Foods
Chwastowska-Siwiecka I, Kaca A, Miciński J.   +2 more
europepmc   +1 more source

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

The symbiotic axis between the acidic tumor microenvironment and cancer stem cells: a driver of malignancy and therapeutic resistance. [PDF]

Front Oncol
Wang Z, Yuan H, Liu M, Yuan J, Chen D.
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Metabolic-inhibitor profiling links phenotype and transcriptome of <i>Lachancea thermotolerans</i> to wine fermentation chemistry. [PDF]

Food Chem (Oxf)
Jimena-López S, Vicente J, Benito S, Marquina D, Santos A.   +4 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

The effect of foliar spraying of naphthalene acetic acid, gibberellic acid, kinetin, putrescine and salicylic acid on physicochemical properties of 'Shahabi' date fruit. [PDF]

Sci Rep
Shahsavar AR, Farkhondeh H, Sayyad-Amin P.   +2 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Microenvironment plays a critical role in modulating tumor cell dormancy: Current perspectives and potential treatment options. [PDF]

World J Clin Oncol
Qian YR, Liu P, Xu H, Lv Y, Zhang XF, Xiang JX.   +5 more
europepmc   +1 more source

pH-Dependent Microenvironmental Ionic Signaling in Pancreatic Ductal Adenocarcinoma. [PDF]

Acta Physiol (Oxf)
Schwab A, Rugi M, Swietach P, Błaszczak W, Novak I, Deshar G, Pedersen SF, Ialchina R, Sandelin A, Yao J, Reshkin SJ, Cardone RA, Carvalho TMA, Arcangeli A, Bouazzi R, D'Alessandro FN, Prevarskaya N, Audero MM, Ouadid-Ahidouch H, Schnipper J, Pardo LA, Shi X, Alves F, Mitręga J, Trauzold A, Hagelund SE, Panyi G, Cozzolino M, Löwik CMWG, Mezzanotte L, McMorrow R, Pahl A, Hechler T, Papacharisi E, Pla AF, Szabo I, Hofschröer V, Pethő Z.   +37 more
europepmc   +1 more source