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Minnesota medicine, 1969 Some of the next articles are maybe not open access.
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Intensive Care Medicine, 2003
The detection of tissue hypoxia and its correction is one of the aim of the hemodynamic monitoring. Classical hemodynamic variable often fail to achieve this goal. Lactate measurements may be a good indicator of tissue hypoxia. Selected review of the articles on lactate in critically ill patients.
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The detection of tissue hypoxia and its correction is one of the aim of the hemodynamic monitoring. Classical hemodynamic variable often fail to achieve this goal. Lactate measurements may be a good indicator of tissue hypoxia. Selected review of the articles on lactate in critically ill patients.
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Enzyme, 1987
For use in screening for disorders of pyruvate metabolism in cultured skin fibroblasts, we developed a sensitive assay method for measuring the rates of decarboxylation of (1-14C)-pyruvate using dichloroacetate (DCA). By this method, disorders of the mechanism of activation of pyruvate dehydrogenase (PDH) were found in 2 of 10 patients with congenital ...
Y, Kuroda +4 more
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For use in screening for disorders of pyruvate metabolism in cultured skin fibroblasts, we developed a sensitive assay method for measuring the rates of decarboxylation of (1-14C)-pyruvate using dichloroacetate (DCA). By this method, disorders of the mechanism of activation of pyruvate dehydrogenase (PDH) were found in 2 of 10 patients with congenital ...
Y, Kuroda +4 more
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The Journal of Pediatrics, 1981
PRIMARY LACTIC ACIDOSIS/LACTIC ACIDURIA occurs in patients with a deficiency of specific enzymes involved in the metabolism of pyruvate, such as pyruvate carboxylase, pyruvate dehydrogenase, and phosphoenolpyruvate carboxykinase, and in other metabolic disorders such as type 1 glycogen storage disease, hereditary fructose intolerance, and disorders of ...
J G, Rogers +3 more
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PRIMARY LACTIC ACIDOSIS/LACTIC ACIDURIA occurs in patients with a deficiency of specific enzymes involved in the metabolism of pyruvate, such as pyruvate carboxylase, pyruvate dehydrogenase, and phosphoenolpyruvate carboxykinase, and in other metabolic disorders such as type 1 glycogen storage disease, hereditary fructose intolerance, and disorders of ...
J G, Rogers +3 more
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Endocrinology and Metabolism Clinics of North America, 1993
Lactic acidosis is the most common metabolic acidosis. At clinical presentation, several causes usually can be identified. The liver is a major site of removal of lactate and hydrogen ions, and abnormalities in the aerobic metabolism of lactate by mitochondria in hepatocytes and other cells may contribute to many clinical conditions in which ...
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Lactic acidosis is the most common metabolic acidosis. At clinical presentation, several causes usually can be identified. The liver is a major site of removal of lactate and hydrogen ions, and abnormalities in the aerobic metabolism of lactate by mitochondria in hepatocytes and other cells may contribute to many clinical conditions in which ...
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Disease-a-Month, 1989
An understanding of the pathophysiology of lactic acidosis is crucial in facilitating the optimal care of critically ill patients. The relevant biochemistry of lactic acidosis is reviewed, and the more controversial aspects relating to the genesis of the acidosis are highlighted.
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An understanding of the pathophysiology of lactic acidosis is crucial in facilitating the optimal care of critically ill patients. The relevant biochemistry of lactic acidosis is reviewed, and the more controversial aspects relating to the genesis of the acidosis are highlighted.
openaire +2 more sources