Identification of the salmonid IL-17A/F1a/b, IL-17A/F2b, IL-17A/F3 and IL-17N genes and analysis of their expression following in vitro stimulation and infection [PDF]
, 2015 Peer ...
Husain, Mansourah +5 more
core +1 more source
Immune modulation by virus-encoded secreted chemokine binding proteins [PDF]
, 2015 Chemokines are chemoattractant cytokines that mediate the migration of immune cells to sites of infection which play an important role in innate and adaptive immunity. As an immune evasion strategy, large DNA viruses (herpesviruses and poxviruses) encode
Alcamí, Antonio +2 more
core +1 more source
Beyond Cell Motility: The Expanding Roles of Chemokines and Their Receptors in Malignancy
Frontiers in Immunology, 2020 The anti-tumor activities of some members of the chemokine family are often overcome by the functions of many chemokines that are strongly and causatively linked with increased tumor progression.
Dina Morein +2 more
doaj +1 more source
The atypical chemokine receptor-2 does not alter corneal graft survival but regulates early stage of corneal graft induced lymphangiogenesis [PDF]
, 2018 Open Access via Springer Compact Agreement Funding: Saving Sight in Grampian provided financial support in the forming of Saving Sight in Grampian funding.
Forrester, John V. +3 more
core +1 more source
The chemokine scavenging receptor D6/ACKR2 is a target of miR-146a in thyroid cancer [PDF]
Genes & Cancer, 2017 We have previously shown that miR-146a, a NF-κB-regulated microRNA, is strongly expressed in human specimens and cell lines derived from anaplastic thyroid carcinomas (ATC) where it mediates some of the NF-κB pro-tumorigenic functions. By using a bioinformatic analysis, we identified the chemokine scavenger receptor D6/ ACKR2 as a target of miR146a in ...
Francesco Pacifico +7 more
openaire +5 more sources
Transfection of Sertoli cells with androgen receptor alters gene expression without androgen stimulation [PDF]
, 2015 Background: Androgens play an important role for the development of male fertility and gained interest as growth and survival factors for certain types of cancer.
Bergmann, M. +8 more
core +3 more sources
Identification of potential biomarkers in donor cows for in vitro embryo production by granulosa cell transcriptomics [PDF]
, 2017 The Ovum Pick Up-In vitro Production (OPU-IVP) of embryos is an advanced reproductive technology used in cattle production but the complex biological mechanisms behind IVP outcomes are not fully understood.
Callesen, Henrik +7 more
core +3 more sources
Expert Review of Clinical Immunology, 2023 ACKR2 is a scavenger for most inflammation-related CC chemokines. This study aimed to assess the pan-cancer prognostic significance of ACKR2 and the genetic and epigenetic mechanisms underlying its dysregulation. Pan-cancer data from The Cancer Genome Atlas (TCGA), Therapeutically Applicable Research to Generate Effective Treatments (TARGET) and The ...
Hongxiu Dong +4 more
openaire +2 more sources
Intrapericardial Administration of Secretomes from Menstrual Blood-Derived Mesenchymal Stromal Cells: Effects on Immune-Related Genes in a Porcine Model of Myocardial Infarction. [PDF]
, 2022 Acute myocardial infarction (AMI) is a manifestation of ischemic heart disease where the immune system plays an important role in the re-establishment of homeostasis.
Blanco, Virginia +11 more
core +1 more source
Genetically encoded intrabody sensors report the interaction and trafficking of β-arrestin 1 upon activation of G protein-coupled receptors [PDF]
, 2020 Agonist stimulation of G protein-coupled receptors (GPCRs) typically leads to phosphorylation of GPCRs and binding to multifunctional proteins called β-arrestins (βarrs).
Baidya, M +11 more
core +1 more source