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Diterpenoids with anti-inflammatory activity from the lateral root of Aconitum carmichaelii debeaux
Phytochemistry, 2022Five undescribed diterpenoids, including two ent-cleistanthane-type diterpenoids aconicleistanthanes A and B, a hetisine-type diterpenoid aconihetisine A, two aconitines-type diterpenoids aconicarmines A and B, and thirteen known diterpenoids alkaloids, were co-isolated from the lateral root of the Aconitum carmichaelii Debeaux (Ranunculaceae).
Hui, Cui +6 more
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First report of aconitum virus 2 infecting Aconitum carmichaelii in North China
Journal of Plant Pathologyexaly +2 more sources
Qualitative and quantitative analysis of aconitine-type and lipo-alkaloids of Aconitum carmichaelii roots [PDF]
Journal of Chromatography A, 2009 By optimizing the extraction and analytical conditions, a reliable and precise HPLC method coupled with photodiode array detection (HPLC-DAD) has been developed for the identification and quantification of three major aconitine-type alkaloids (aconitine, mesaconitine, hypaconitine) in the roots of Aconitum carmichaelii Debeaux. The qualitative analysis
Csupor Dezső +5 more
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Four New Diterpenoid Alkaloids from the Roots of Aconitum carmichaelii
Chemistry & Biodiversity, 2018Aconitum carmichaelii Debeaux is a widely used traditional Chinese medicine and an important source of clinical drugs, of which the parent and lateral roots are known as ‘Chuanwu’ and ‘Fuzi’, respectively. Four new C19‐diterpenoid alkaloids, carmichasines A – D (1 – 4), were isolated from the roots of Aconitum carmichaelii, together with twelve known ...
Yu, Li +3 more
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Fitoterapia, 2021
Fuzi, a well-known traditional Chinese medicine developed from the lateral roots of Aconitum carmichaelii Debx., has been widely used for the treatment of heart failure. In order to search for active compounds from Fuzi, a phytochemical study was performed, which resulted in the isolation of 14 aminoalcohol-diterpenoid alkaloids, including one new ...
Xiao-Ya, Wang +9 more
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Fuzi, a well-known traditional Chinese medicine developed from the lateral roots of Aconitum carmichaelii Debx., has been widely used for the treatment of heart failure. In order to search for active compounds from Fuzi, a phytochemical study was performed, which resulted in the isolation of 14 aminoalcohol-diterpenoid alkaloids, including one new ...
Xiao-Ya, Wang +9 more
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Potentially Cardiotoxic Diterpenoid Alkaloids from the Roots of Aconitum carmichaelii
Journal of Natural Products, 2019Aconitum carmichaelii is a traditional Chinese herbal medicine used for the treatment of pain and inflammation in the joints. However, the strong cardiotoxicity hinders its use. Although diester- and monoester-type diterpenoids, e.g., aconitine, mesaconitine, and hypacaonitine, are commonly considered as the toxic components, the toxicity of A ...
Xingxing Zong +6 more
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Aromatic acid derivatives from the lateral roots of Aconitum carmichaelii
Journal of Asian Natural Products Research, 2014Seven new aromatic acid derivatives (1-7), together with five known analogs, were isolated from the lateral roots of Aconitum carmichaelii. Structures of the new compounds were determined by spectroscopic and chemical methods as 4-methyl ( - )-(R)-hydroxyeucomate (1), 4-butyl ( - )-(R)-hydroxyeucomate (2), 4-butyl-1-methyl (+)-(R)-2-O-(4'-hydroxy-3 ...
Zhi-Bo, Jiang +7 more
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Two new pyrazines from the parent roots of Aconitum carmichaelii
Biochemical Systematics and Ecology, 2013Two new pyrazines, aconicarpyrazine A (1) and aconicarpyrazine B (2), together with five known heterocyclic compounds: adenosine (3), uridine (4), hypoxanthine (5), nicotinamide (6), and uracil (7), were isolated from the parent roots of Aconitum carmichaelii. The structures of these alkaloids were elucidated by spectroscopic analysis, including 2D NMR
Li Guo +7 more
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Aconitum carmichaelii Debeaux, cultivated as a medicinal plant in western China
Genetic Resources and Crop Evolution, 2016Large-scale cultivation of Aconitum carmichaelii Debeaux has been carried out on medicinal plant farms in western China for over 1000 years. After detoxification, the fleshy roots are officially used as aconite in herbal medicine.
Ma Yu +4 more
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Specialized metabolites of the endophyte Annulohypoxylon areolatum hosted by Aconitum carmichaelii
PhytochemistrySeven previously undescribed compounds, including one amino acid hybrid sesquiterpene areolatol A (1), two unusual natural sesquiterpenoid skeleton areolatones A-B (2-3) and four benzo[j]fluoranthene areolaranes A-D (4-7) were characterized from Annulohypoxylon areolatum.
Cheng-Yao Wang +11 more
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