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Memories of Past Presidents

Journal of College Orientation, Transition, and Retention, 2007
Six of NODA's past presidents shared their thoughts about NODA's history in a recent leadership survey compiled by Maria Sedotti of the University of Connecticut.
Denise L. Rode
doaj   +1 more source

Antibodies against citrullinated proteins of IgA isotype are associated with progression to rheumatoid arthritis in individuals at-risk

RMD Open, 2023
Objective Events triggering disease outbreak in individuals at-risk for rheumatoid arthritis (RA at-risk) remain unclear, and the role of the various anticitrullinated protein antibody (ACPA) isotypes in this process is still to be established.
Georg Schett, Holger Bang, Arnd Kleyer, Guenter Steiner, Daniela Sieghart, Fabian Hartmann, Maria V Sokolova, Ulrike Steffen   +7 more
doaj   +1 more source

The ACPA recognition profile and subgrouping of ACPA-positive RA patients

Annals of the Rheumatic Diseases, 2012
Anticitrullinated protein antibodies (ACPA) are the most predictive factor for the development of rheumatoid arthritis (RA). Epitope spreading towards more citrullinated epitopes occurs before the onset of RA. Here, the authors investigated whether specific epitope recognition allows the identification of specific RA subgroups and whether it is ...
Willemze, A., Bohringer, S., Knevel, R., Levarht, E.W.N., Stoeken-Rijsbergen, G., Houwing-Duistermaat, J.J., Helm-van Mil, A.H.M. van der, Huizinga, T.W.J., Toes, R.E.M., Trouw, L.A.   +9 more
openaire   +4 more sources

Early intensive treatment normalises excess mortality in ACPA-negative RA but not in ACPA-positive RA [PDF]

Annals of the Rheumatic Diseases, 2020
With great interest, we read the recently published report by Poppelaars et al in which no excess mortality was observed in 155 patients with rheumatoid arthritis (RA) from the COmbinatie therapie Bij Rheumatoide Artritis (COBRA)-trial, who received early intensive treatment, compared with the general population (Standardised mortality rate (SMR) 0.80 (
Matthijssen, X.M.E., Huizinga, T.W.J., Niemantsverdriet, E., Helm-van Mil, A.H.M. van der   +3 more
openaire   +4 more sources

AB0012 In the elderly acpa-negative ra is more prevalent than acpa-positive ra while the composition of the acpa-response appears identical [PDF]

Annals of the Rheumatic Diseases, 2017
Background Rheumatoid arthritis (RA) consists of two syndromes, one autoantibody-positive and one autoantibody-negative. This multi-cohort study assessed the age of onset in relation to the presence of autoantibodies. The association with characteristics of the anti-citrullinated protein antibodies (ACPA)-response was also explored.
D Boeters, L Mangnus, S Ajeganova, E Lindqvist, B Svensson, R Toes, L Trouw, T Huizinga, F Berenbaum, J Morel, S Rantapää-Dahlqvist, A van der Helm-van Mil   +11 more
openaire   +1 more source

MRI-detected osteitis is not associated with the presence or level of ACPA alone, but with the combined presence of ACPA and RF [PDF]

Arthritis Research & Therapy, 2016
In rheumatoid arthritis (RA) bone marrow edema (BME, osteitis) and anti-citrullinated protein antibodies (ACPA) are associated with radiographic progression. ACPA have been associated with BME, but it is unknown if this association is confined to ACPA and BME.
Boeters, D.M., Nieuwenhuis, W.P., Verheul, M.K., Newsum, E.C., Reijnierse, M., Toes, R.E.M., Trouw, L.A., Helm-van Mil, A.H.M. van der   +7 more
openaire   +4 more sources

CCR6+ Th cell populations distinguish ACPA positive from ACPA negative rheumatoid arthritis [PDF]

Arthritis Research & Therapy, 2015
Patients with rheumatoid arthritis (RA) can be separated into two major subpopulations based on the absence or presence of serum anti-citrullinated protein antibodies (ACPAs). The more severe disease course in ACPA(+) RA and differences in treatment outcome between these subpopulations suggest that ACPA(+) and ACPA(-) RA are different disease subsets ...
Paulissen, Sandra M.J., van Hamburg, Jan Piet, Davelaar, Nadine, Vroman, Heleen, Hazes, Johanna M.W., de Jong, Pascal H.P., Lubberts, Erik   +6 more
openaire   +2 more sources

Association between inflammatory cytokines and immune-checkpoint molecule in rheumatoid arthritis.

PLoS ONE, 2021
BackgroundAnti-citrullinated peptide antibodies (ACPA) and inflammatory cytokines play important roles in the development of rheumatoid arthritis (RA). T cell immunoglobulin and mucin-domain containing-3 (TIM-3) is an immune-checkpoint molecule involved ...
Haruki Matsumoto, Yuya Fujita, Tomoyuki Asano, Naoki Matsuoka, Jumpei Temmoku, Shuzo Sato, Makiko Yashiro-Furuya, Kohei Yokose, Shuhei Yoshida, Eiji Suzuki, Toru Yago, Hiroshi Watanabe, Atsushi Kawakami, Kiyoshi Migita   +13 more
doaj   +2 more sources

OP0314 B cell phenotype and function in the synovium of acpa+ and acpa- rheumatoid arthritispatients [PDF]

Annals of the Rheumatic Diseases, 2018
Background Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease of unknown and complex etiology with severe detrimental effects for the patient’s quality of life. While rheumatoid factors (RF) and anti-citrulinated protein antibodies (ACPA) have been used extensively for the diagnosis of RA, no clear mechanism of action towards ...
A. Floudas, M. Biniecka, C. Low, D.J. Veale, U. Fearon   +4 more
openaire   +1 more source

Interaction of CB1 receptor agonist arachidonylcyclopropylamide with behavioural sensitisation to morphine in mice

Veterinární Medicína, 2014
Activities of the endocannabinoid system are believed to be substantially involved in psychostimulant and opioid addiction. Nevertheless, interactions between cannabinoid and opioid systems are not yet fully understood. Thus, the aim of the present study
L. Landa, K. Slais, A. Machalova, A. Sulcova   +3 more
doaj   +1 more source