Results 31 to 40 of about 5,038 (172)

MRI-detected osteitis is not associated with the presence or level of ACPA alone, but with the combined presence of ACPA and RF [PDF]

Arthritis Research & Therapy, 2016
In rheumatoid arthritis (RA) bone marrow edema (BME, osteitis) and anti-citrullinated protein antibodies (ACPA) are associated with radiographic progression. ACPA have been associated with BME, but it is unknown if this association is confined to ACPA and BME.
Boeters, D.M., Nieuwenhuis, W.P., Verheul, M.K., Newsum, E.C., Reijnierse, M., Toes, R.E.M., Trouw, L.A., Helm-van Mil, A.H.M. van der   +7 more
openaire   +6 more sources

Autoantikörper und die autoreaktive Immunantwort: ACPA sind mehr als nur ACPA [PDF]

, 2020
The immune response against posttranslationally modified (PTM) antigens, in particular the generation of anti-citrullinated protein antibodies (ACPA), is a very specific hallmark of rheumatoid arthritis. The factors that initiate this immune response and
Scherer, H.U.
core   +1 more source

One‐Pot Synthesis of Aqueous PEDOT‐Based Conductive Inks via Sequential RAFT/Oxidative Polymerization

Angewandte Chemie, EarlyView.
We developed a fast, aqueous one‐pot synthesis for PEDOT:PSTFSI, combining sequential reversible addition–fragmentation chain‐transfer (RAFT) and oxidative polymerization. This method eliminates toxic solvents and purification steps, achieving full monomer conversion in under 3 h.
Fantine Negny, Melanie Bousquet, Benjamin Cabannes‐Boué, Pierre‐Yves Dugas, Lionel Hirsch, Thiago R. Guimaraes, Eric Cloutet   +6 more
wiley   +2 more sources

Influence of Oral Microbiota on the Presence of IgA Anti-Citrullinated Protein Antibodies in Gingival Crevicular Fluid

Frontiers in Oral Health, 2022
IntroductionThe relation between rheumatoid arthritis (RA) and periodontitis (PD) has been investigated ever since the discovery of the citrullinating enzyme peptidyl arginine deaminase presents in the oral bacterium Porphyromonas gingivalis.
Menke J. de Smit, Menke J. de Smit, Poerwati Soetji Rahajoe, Elisabeth Raveling-Eelsing, Paola Lisotto, Hermie J. M. Harmsen, Nyoman Kertia, Arjan Vissink, Johanna Westra   +8 more
doaj   +1 more source

Interaction of CB1 receptor agonist arachidonylcyclopropylamide with behavioural sensitisation to morphine in mice

Veterinární Medicína, 2014
Activities of the endocannabinoid system are believed to be substantially involved in psychostimulant and opioid addiction. Nevertheless, interactions between cannabinoid and opioid systems are not yet fully understood. Thus, the aim of the present study
L. Landa, K. Slais, A. Machalova, A. Sulcova   +3 more
doaj   +1 more source

Autoantibodies to citrullinated proteins: ACPA

Autoimmunity, 2005
Anti-perinuclear factor and anti-keratin antibodies have long been known to be specifically associated with rheumatoid arthritis (RA). They were first demonstrated to target various forms of (pro)filaggrin, a protein of stratified epithelia. Then, they were found to belong to a single family of autoantibodies targeting proteins that bear peptidic ...
Christian, Vincent, Leonor, Nogueira, Cyril, Clavel, Mireille, Sebbag, Guy, Serre   +4 more
openaire   +2 more sources

Association between inflammatory cytokines and immune-checkpoint molecule in rheumatoid arthritis.

PLoS ONE, 2021
BackgroundAnti-citrullinated peptide antibodies (ACPA) and inflammatory cytokines play important roles in the development of rheumatoid arthritis (RA). T cell immunoglobulin and mucin-domain containing-3 (TIM-3) is an immune-checkpoint molecule involved ...
Haruki Matsumoto, Yuya Fujita, Tomoyuki Asano, Naoki Matsuoka, Jumpei Temmoku, Shuzo Sato, Makiko Yashiro-Furuya, Kohei Yokose, Shuhei Yoshida, Eiji Suzuki, Toru Yago, Hiroshi Watanabe, Atsushi Kawakami, Kiyoshi Migita   +13 more
doaj   +2 more sources

Analysis of ACPA positivity and ACPA fine specificities in a large Swedish twin cohort (TwinGene) [PDF]

Annals of the Rheumatic Diseases, 2012
Backgroundand objectives Genetic factors play a significant role in the variance of susceptibility for anticitrullinated protein antibodies (ACPA)-positive RA (Woude et al 2009). The authors wanted to study ACPA positivity as an entity and aimed to investigate the influence of genetic and environmental factors for ACPA positivity using a twin study ...
Aase Haj Hensvold, Patrik K E Magnusson, Monika Hansson, Lena Israelsson, Cecilia Carlens, Rikard Holmdahl, Per-Johan Jakobsson, Johan Askling, Tomas Ekström, Vivianne Malmström, Lars Klareskog, Anca Irinel Catrina   +11 more
openaire   +1 more source

Multicentre study to improve clinical interpretation of rheumatoid factor and anti-citrullinated protein/peptide antibodies test results

RMD Open, 2022
Background Rheumatoid factor (RF) and anti-citrullinated protein/peptide antibodies (ACPA) are important biomarkers for diagnosis of rheumatoid arthritis (RA). However, there is poor harmonisation of RF and ACPA assays.
Lieve Van Hoovels, Xavier Bossuyt, Daniel Aletaha, Christopher Sjöwall, Stefanie Van den Bremt, Diego Kyburz, Alf Kastbom, Peggy Jacques, Laura Bogaert, Carolien Bonroy, Bert Vander Cruyssen, Ingmar Heijnen, Patrick Verschueren, Charlotte Dahle, Rille Pullerits, Saša Čučnik, Guenter Steiner, Daniela Sieghart, Eszter Nagy, Luca Bernasconi, Farid Benkhadra, Ann Van Liedekerke, Geert Vanheule, Johan Robbrecht, Lucy Studholme, Claudine Wirth, Rüdiger Müller, Rok Ješe, Boja Jovancevic, Emese Kiss   +29 more
doaj   +1 more source

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis [PDF]

, 2010
BackgroundRheumatoid arthritis (RA) can be divided into two major subsets based on the presence or absence of antibodies to citrullinated peptide antigens (ACPA).
Klareskog, Lars, R. T. H. Ong, L. Padyukov, Ong, Rick TH, M. Seielstad, L. Alfredsson, Padyukov, Leonid, Ong, Rick T. H., Ding, Bo, Rönnelid, Johan, B. Ding, Seielstad, Mark, Seddighzadeh, Maria, Rönnelid, Johan,, null null, M. Seddighzadeh, J. Ronnelid, Alfredsson, Lars, Group, the Epidemiological Investigation of Rheumatoid Arthritis Study, L. Klareskog   +19 more
core   +1 more source