Development of Radiolabeled Membrane Type-1 Matrix Metalloproteinase Activatable Cell Penetrating Peptide Imaging Probes [PDF]
Molecules, 2015 Membrane type-1 matrix metalloproteinase (MT1-MMP or MMP-14) plays an important role in adverse cardiac remodelling. Here, we aimed to develop radiolabeled activatable cell penetrating peptides (ACPP) sensitive to MT1-MMP for the detection of elevated ...
Sander M. J. van Duijnhoven +3 more
doaj +4 more sources
Abstract A005: MMP FRET ACPP imaging of mammary tumors in a mouse model of postmenopausal obesity
Molecular Cancer Research, 2013 Abstract Obesity in postmenopausal women is a risk factor for breast cancer. Since 25-30% of women in the USA are obese, the public health implications of obesity and breast cancer are immense. Activation of inflammatory pathways is one plausible mechanism underlying the association between obesity and increased breast cancer risk.
Crisp, Jessica L +5 more
openaire +4 more sources
Métodos de reducción de dimensionalidad: Análisis comparativo de los métodos APC, ACPP y ACPK
Uniciencia, 2016 Los métodos de reducción de dimensionalidad son algoritmos que mapean el conjunto de los datos a subespacios derivados del espacio original, de menor dimensión, que permiten hacer una descripción de los datos a un menor costo.
Jorge Arroyo-Hernández
doaj +2 more sources
SHAP-Based Identification of Potential Acoustic Biomarkers in Patients with Post-Thyroidectomy Voice Disorder [PDF]
DiagnosticsObjective: The objective of this study was to identify potential robust acoustic biomarkers for functional post-thyroidectomy voice disorder (PTVD) that may support early diagnosis and personalized treatment strategies, using acoustic analysis and ...
Salih Celepli +9 more
doaj +2 more sources
High‐Throughput Tiling of Essential mRNAs Increases Potency of Antisense Antibiotics [PDF]
Advanced ScienceAntimicrobial resistance is outpacing drug discovery, creating an urgent need for precision‐based strategies to counteract resistant pathogens. Peptide nucleic acid (PNA)‐based antisense molecules offer a promising approach by selectively inhibiting ...
Giorgia Danti +3 more
doaj +2 more sources
A Rare Case of Atypical Choroid Plexus Papilloma in an Adult Male Patient: A Case Report [PDF]
Case Reports in PathologyChoroid plexus tumors (CPTs) are rare neoplasms. Patient presentation varies depending on the location of the lesions. Gross total resection of primary lesions remains the gold standard for surgical treatment of CPTs.
Abebe Melis Nisiro +1 more
doaj +2 more sources
Leptomeningeal Dissemination in Choroid Plexus Tumors: Magnetic Resonance Imaging Appearance and Risk Factors [PDF]
ChildrenBackground: Intracranial choroid plexus tumors (CPT) are rare and primarily affect young children. Leptomeningeal dissemination (LMD) has been reported not only in high-grade choroid plexus carcinoma (CPC) but also in lower histological grades; however ...
Daniel Nunes do Espirito Santo +13 more
doaj +2 more sources
Diagnostic Challenges in Choroid Plexus Tumours. [PDF]
Neuropathol Appl NeurobiolIn this review, we summarise the diagnostic spectrum of choroid plexus tumours, highlight key age‐dependent differential diagnoses across infants, children/adolescents and adults, and outline how histopathology, immunohistochemistry and molecular profiling support accurate tumour classification.
Thomas C, Hasselblatt M.
europepmc +2 more sources
Tetranucleotide repeat polymorphism at the human prostatic acid phosphatase (ACPP) gene [PDF]
Nucleic Acids Research, 1991 Mihael Polymeropoulos, Carl R Merril
exaly +3 more sources
Tetranucleotide repeat polymorphism at the ACPP locus
Nucleic Acids Research, 1991 Peter Humphries, P McWilliam
exaly +4 more sources