Variants in ACPP are associated with cerebrospinal fluid Prostatic Acid Phosphatase levels [PDF]
Prostatic Acid Phosphatase (PAP) is an enzyme that is produced primarily in the prostate and functions as a cell growth regulator and potential tumor suppressor. Understanding the genetic regulation of this enzyme is important because PAP plays an important role in prostate cancer and is expressed in other tissues such as the brain.We tested ...
Staley, Lyndsay A. +6 more
openaire +2 more sources
Cell-penetrating peptides and their analogues as novel nanocarriers for drug delivery [PDF]
Introduction: The impermeability of biological membranes is a major obstacle in drug delivery; however, some peptides have transition capabilities of biomembranes.
Samira Jafari +2 more
doaj +1 more source
Membrane type-1 matrix metalloproteinase (MT1-MMP or MMP-14) plays an important role in adverse cardiac remodelling. Here, we aimed to develop radiolabeled activatable cell penetrating peptides (ACPP) sensitive to MT1-MMP for the detection of elevated ...
Sander M. J. van Duijnhoven +3 more
doaj +1 more source
Tumor microenvironment-responsive metal nanotherapeutics for breast cancer chemo-/immunotherapy
Many metal complexes not only had excellent cytotoxic antitumor effects but also could function as a positive immunomodulatory to improve antitumor effects by modifying the local tumor microenvironment.
Jinggong Liu +10 more
doaj +1 more source
Ancient Chinese poetry and prose (ACPP) are the essence of traditional Chinese culture and also literary gems of the world. Despite the long tradition of previous Chinese Presidents using ACPP in their political addresses, the translation work on the ...
Qiannan Liu, Xiaolong Li
doaj +1 more source
Antisense PNA accumulates in Escherichia coli and mediates a long post-antibiotic effect [PDF]
Antisense agents that target growth-essential genes display surprisingly potent bactericidal properties. In particular, peptide nucleic acid (PNA) and phosphorodiamidate morpholino oligomers linked to cationic carrier peptides are effective in time kill ...
Behmanesh, Mehrdad +9 more
core +2 more sources
Is the strong-interaction proton-proton scattering length renormalization scale dependent in effective field theory? [PDF]
It is shown that the strong-interaction ${}^1S_0$ proton-proton scattering length in very low-energy effective field theory does not depend on the renormalization scale, if the electromagnetic interaction is "switched off" consistently.Comment: 9 pages ...
Gegelia, J.
core +1 more source
Transcriptome analysis of Listeria monocytogenes exposed to biocide stress reveals a multi-system response involving cell wall synthesis, sugar uptake, and motility [PDF]
peer-reviewedListeria monocytogenes is a virulent food-borne pathogen most often associated with the consumption of “ready-to-eat” foods. The organism is a common contaminant of food processing plants where it may persist for extended periods of time.
Aidan eCasey +6 more
core +4 more sources
The antioxidant activity of the aqueous crude extract of Ocimum gratissimum Linn. leaf on the basal and traumatized (cadmium-induced) serum levels of alkaline phosphatase (ALP), total acid phosphatase (ACPT) and prostatic acid phosphatase (ACPP) of the ...
JS Aprioku, AW Obianime
doaj +3 more sources
Clinical Features and Prognostic Risk Factors of Choroid Plexus Tumors in Children
Background: Decision-making concerning the treatment of choroid plexus tumor (CPT) in pediatric patients remains a topic of considerable debate. The aim of this work was to describe clinical features and prognostic risk factors of CPT in the pediatric ...
Wen-Jian-Long Zhou +9 more
doaj +1 more source

