Results 101 to 110 of about 5,616 (261)
Clinical Pharmacology in Drug Development, EarlyView.Abstract Mocravimod, a novel immunomodulator targeting sphingosine‐1‐phosphate receptor (S1PR), is being developed as a maintenance treatment for patients with acute myeloid leukemia undergoing allogeneic hematopoietic cell transplantation. Preclinical data suggested that cytochrome (CYP) 3A4 is the primary enzyme involved in mocravimod metabolism.
Dymphy R. Huntjens +2 more
wiley +1 more source
Revolution, death , transformation and art: Delacroix's 'Scenes from the Massacres at Chios' [PDF]
, 2013 “Of all foreign artists, Delacroix is the one whose name is most closely associated with the Greek Revolution of 1821.” By examining this famous Romantic painting, 'Scenes from the Massacres at Chios', it will become apparent that the particular ...
Devetzidis, Areti
core
Navigating the Genetic Risk of Chemotherapy‐Induced Hearing Loss in the Stria Vascularis
Clinical Pharmacology &Therapeutics, EarlyView.Cisplatin is a chemotherapy drug that causes permanent hearing loss by damaging a critical tissue lining the inner ear, called the stria vascularis (SV). Currently, the molecular mechanisms of SV damage are largely unknown and the incidence of ototoxicity in patients cannot be reliably predicted.
Tara Lazetic +4 more
wiley +1 more source
ORGANIZATIONAL SILENCE AND ITS IMPACT ON A LOW LEVEL OF JOB PERFORMANCE [PDF]
The study aimed to identify the relationship between organizational silence in its three dimensions (defensive silence, acquiescent silence, and social silence).
Hameed Alsady, Soulaf Abdalqadir
core +1 more source
Major Adverse Cardiac Events with Ondansetron: A Systematic Review
Clinical Pharmacology &Therapeutics, EarlyView.Evidence base: 170 randomized trials, 23,421 adults, predominantly single‐dose IV ondansetron, mean follow‐up 20 days. Observed outcomes: Major adverse cardiac events were rare, no ventricular arrhythmias or torsades de pointes observed. Conclusion: Ondansetron was not associated with increased mortality or serious cardiac arrhythmias in adult ...
Michael Cristian Garcia +11 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Cannabidiol (CBD) is one of the most abundant bioactive cannabinoids. Research has demonstrated CBD’s ability to inhibit metabolic enzymes like cytochrome P450 (CYP) and UDP‐glucuronosyltransferase (UGT), potentially leading to drug interactions. However, clinical knowledge gaps remain, particularly with regard to drugs that are more commonly taken by ...
Pablo Salcedo +11 more
wiley +1 more source
The relationship between toxic leadership and organizational performance: the mediating effect of nurses' silence. [PDF]
BMC Nurs, 2023 Farghaly Abdelaliem SM, Abou Zeid MAG.
europepmc +1 more source
Corporate Social Responsibility and Environmental Management, EarlyView.ABSTRACT This study investigates how proactive environmental strategy, operationalized through company environmental strategy (CES) and green marketing strategy (GMS), shapes green brand competitiveness (GBC) and new green product success (NGPS) via green brand positioning (GBP).
Haozhe Ma, Arnaldo Coelho, Célia Santos
wiley +1 more source
CAQ Corner: Immune‐mediated complications
, 2022 Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley +1 more source
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.This paper explores global solar PV deployment, cost trends, and grid integration challenges in 2025. It examines the role of energy storage in firming solar output and supporting electric vehicle (EV) growth, alongside policy shifts, investment flows, and technological innovations.
Ehsan Rezaee, S. Ravi P. Silva
wiley +1 more source