Results 211 to 220 of about 3,156,736 (262)

Analysis of the Mediating Role of Cytokines in the Relationship Between Nonalcoholic Fatty Liver Disease and Cognitive Impairment After Ischemic Stroke

Brain and Behavior, Volume 16, Issue 10, October 2026.
This article reveals the mediating role of cytokine levels between non‐alcoholic fatty liver disease and post‐stroke cognitive impairment, providing new therapeutic targets for post‐stroke cognitive dysfunction. Abstract Objective To explore whether nonalcoholic fatty liver disease (NAFLD) is associated with poststroke cognitive impairment (PSCI) and ...
Xin Du, Jingwei Li
wiley   +1 more source

Diagnostic Performance of Bronchoalveolar Lavage Fluid Metagenomic Next‑generation Sequencing versus Conventional Microbiological Tests in Immunocompromised and Immunocompetent Patients with Pulmonary Infection. [PDF]

Infect Drug Resist
Song Y, Xu C, Zu F, Dong R, Yang H.
europepmc   +1 more source

Adaptogenic‐Like Potential of Bauhinia forficata Leaf Extracts: Behavioral and Oxidative Outcomes in an Acute Stress Mouse Model

Brain and Behavior, Volume 16, Issue 10, October 2026.
Graphical abstract ilustrates the adaptogenic‐like potential of crude extracts (CEs) and dichloromethane (DCM) fraction from B. forficata leaves in an acute stress mouse model. C57BL/6J/UFU mice were submitted to a social isolation protocol and both CE (30 mg/kg) and DCM (10 mg/kg) significantly reduced immobility in the forced swim test and increased ...
Sofia Alencar Lafetá, Thiago Neves Vieira, Rodrigo Rodrigues Franco, Ana Claudia Gontijo Couto, Vinicius Prado Bittar, Maria Sol Peña Carrillo, Renata Roland Teixeira, André Luis Lopes Saraiva, Allisson Benatti Justino, Tamara Silva, Veridiana de Melo Rodrigues Ávila, Foued Salmen Espíndola, Cássia Regina Silva   +12 more
wiley   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

Biological Reviews, Volume 101, Issue 5, Page 2408-2426, October 2026.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater, Adam Dušek, Aleksandra Bartelik, Silvia Mandillo, Elisabetta Golini, Mara Rigamonti, Rasneer Sonia Bains, Hamish Forrest, Marion Rivalan, Melissa Long, Anna Kiryk, Lars Lewejohann, Nuno Henrique Franco   +12 more
wiley   +1 more source

Relapse in childhood B-cell precursor acute lymphoblastic leukemia: insights from transcriptomic signatures of diagnostic bone marrow. [PDF]

Front Oncol
Oh L, Azanan MS, Ariffin H.
europepmc   +1 more source

Impact of p53 Target Genes on Drug Resistance in TP53‐Mutated B‐Cell Precursor Acute Lymphoblastic Leukemia

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT TP53 mutations are linked to poor prognoses in B‐cell precursor acute lymphoblastic leukemia (BCP‐ALL), indicating that specific p53 target genes may contribute to drug resistance. Although the impact of specific genetic alterations on drug sensitivity has been reported in BCP‐ALL, the effects of TP53 mutations on sensitivity to individual ...
Thao T. T. Nguyen, Minori Tamai, Koshi Akahane, Chiaki Komatsu, Keiko Kagami, Xuekang Qi, Luay Aswad, Kunio Miyake, Shin Kasai, Shinpei Somazu, Atsushi Watanabe, Kumiko Goi, Koichi Oshima, Hiroshi Imanaga, Yuichiro Semba, Masashi Sanada, Janne Lehtiö, Hiroaki Goto, Masayoshi Minegishi, Toshiya Inaba, Shotaro Iwamoto, Takahiro Maeda, Rozbeh Jafari, Takeshi Inukai   +23 more
wiley   +1 more source

A serum proteomics‐based predictive model for steroid‐resistant immune checkpoint inhibitor associated myocarditis

Clinical and Translational Medicine, Volume 16, Issue 10, October 2026.
The research methods and clinical applications of this predictive score. (1) A pretreatment serum protein‐based score was established and externally validated to predict srICIAM. (2) The post‐treatment trajectory of IL‐22RA1 differed between patients with ssICIAM and srICIAM.
Yerui Zhang, Yihan Li, Jian Zhang, Xiaozhen He, Yihui Shen, Yuchen Xu, Hui Zhang, Jianan Pan, Xuejun Wang, Shilong Zhang, Yan Wang, Leilei Cheng   +11 more
wiley   +1 more source

When Steroids Backfire: A Case of Hyperosmolar Hyperglycemic State, Pneumocystis Pneumonia, and Cauda Equina Syndrome. [PDF]

Cureus
Grondel BT, Patel N, Talone C, Vanderrijst N.   +3 more
europepmc   +1 more source

Gut Microbiota‐Dependent Tryptophan Metabolism Drives the Therapeutic Effects of Baitouweng Tang in Colitis via the AhR Pathway

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
Baitouweng Tang alleviates colitis symptoms in mice by regulating the structure and diversity of gut microbiota, increasing the content of gut microbiota‐related tryptophan metabolites, activating AhR, inhibiting the release of inflammatory mediators, and improving intestinal homeostasis.
Chun Niu, Yongli Hua, Jianguo Kang, Fang Li, Baoxia Chen, Rongxia Guo, Yanming Wei   +6 more
wiley   +1 more source

Targeting nuclear receptors in muscular dystrophies and regenerative myogenesis. [PDF]

Front Cell Dev Biol
Mann E, Vu H, Narkar VA, Liu Y.
europepmc   +1 more source