Results 231 to 240 of about 3,156,736 (262)

Current concepts in glucocorticoid resistance

Steroids, 2012
Nan Yang, David W. Ray, Laura C Matthews
exaly   +2 more sources

Tissue glucocorticoid resistance/hypersensitivity syndromes

Journal of Steroid Biochemistry and Molecular Biology, 2003
Georgios P. Chrousos, Marco Mirani
exaly   +2 more sources

Acquired Resistance to Bortezomib in Human RPMI-8226 Multiple Myeloma Cells: Molecular Characterization, Cross-Resistance with Other Proteasome Inhibitors but Marked Sensitization to Glucocorticoids

Blood, 2008
Abstract The proteasome inhibitor bortezomib (BTZ, PS-341, Velcade®) has proven to be an effective drug in the treatment of multiple myeloma (MM) patients, both in first line as in refractory disease. However, emergence of drug resistance, for which the molecular mechanism(s) remain elusive, can hamper its clinical efficacy. Recently, we
Jacqueline Cloos, Gerrit Jansen, Sonja Zweegman, Bauke Ylstra, Serge Smeets, Uzma Yaqub, Katarina Vojtekova, Ina van Zantwijk, Nynke van den Berg, Gertjan L Kaspers, Niels E Franke   +10 more
openaire   +1 more source

A miR‐29a‐driven negative feedback loop regulates peripheral glucocorticoid receptor signaling

The FASEB Journal, 2019
The glucocorticoid receptor (GR) represents the crucial molecular mediator of key endocrine, glucocorticoid hormone–dependent regulatory circuits, including control of glucose, protein, and lipid homeostasis.
C. Glantschnig, M. Koenen, Manuel Gil-Lozano, M. Karbiener, Ines Pickrahn, Jasmine Williams‐Dautovich, Rucha A Patel, Carolyn L. Cummins, M. Giroud, Götz Hartleben, E. Vogl, M. Blüher, J. Tuckermann, Henriette Uhlenhaut, S. Herzig, M. Scheideler   +15 more
semanticscholar   +1 more source

[Advances in the Treatment of Glucocorticoid Resistance and Relapsed Immune Thrombocytopenia --Review].

Zhongguo shi yan xue ye xue za zhi, 2023
Hui Pan, R. Wen, Zhi-Gang Yang
semanticscholar   +1 more source

Generalized and tissue specific glucocorticoid resistance

Molecular and Cellular Endocrinology, 2021
Clarissa Silva Martins, Margaret de Castro   +1 more
exaly  

Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis

Cell Metabolism, 2021
Karolien De Bosscher, Claude Libert, Peter Carmeliet   +2 more
exaly  

In silico bioinformatics analysis for identification of differentially expressed genes and therapeutic drug molecules in Glucocorticoid-resistant Multiple myeloma

Medical Oncology, 2022
Somnath Ghosal, S. Banerjee
semanticscholar   +1 more source

Mechanisms of Glucocorticoid Response and Resistance in Lymphoid Malignancies

Resistance to Targeted Anti-Cancer Therapeutics, 2019
Lauren K. Meyer, M. Hermiston
semanticscholar   +1 more source

Inflammatory cellular phenotypes and molecular mechanisms of glucocorticoid resistance in patients with bronchial asthma.

Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 2013
Y. Matsumura
semanticscholar   +1 more source