Results 41 to 50 of about 2,391 (154)

Lumbar spinal stenosis: the reliability, sensitivity and specificity of the nerve root sedimentation sign [PDF]

, 2015
Introduction: Lumbar spinal stenosis (LSS) is a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar vertebra.
Azizan, Asrul Fahmi
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High Occurrence of a Missense Variant (c.471C>A) in the FGF23 Gene Related to Hyperostosis–Hyperphosphatemia Syndrome With a Possible Founder Effect

Human Mutation, Volume 2025, Issue 1, 2025.
Background: The autosomal recessive metabolic disorder hyperostosis–hyperphosphatemia syndrome (HHS) is characterized by hyperphosphatemia, hyperostosis, and recurrent bone lesions. Patients may develop ectopic and vascular calcification and may present diaphyseal pain of the long bones that is misdiagnosed as osteomyelitis.
Maryam Sedghi, Elika Esmaeilzadeh Gharehdaghi, Vahid Ziaee, Farzaneh Abbasi, Hamid Reza Aghaei Meybodi, Elina Smiley, Mehrzad Mehdizadeh, Seyyed Reza Raeeskarami, Nahid Aslani, Sahar Naderi Shiran, Mehdi Vafadar, Mahsa M. Amoli, Aziz ur Rehman Aziz   +12 more
wiley   +1 more source

Multiomics Identifies Potential Biomarkers in Ankylosing Spondylitis Bone Formation

Human Mutation, Volume 2025, Issue 1, 2025.
Objective: Ankylosing spondylitis (AS) is a long‐term inflammatory condition characterized by intricate pathogenesis and significant genetic predisposition. Current treatment methods cannot completely halt the progression of the disease. The purpose of this research is to discover possible therapeutic targets for AS by integrating Mendelian ...
Lu Yang, Chunping Bo, Meiqi Chen, Bozhen Chen, Rui Zeng, Yingyan Zhou, Haifang Du, Xiaohong He, Minghua Ren   +8 more
wiley   +1 more source

Magnetic resonance imaging findings in epileptic cats with a normal interictal neurological examination:188 cases [PDF]

, 2017
Epilepsy is a common neurological condition in dogs and cats. Although anincreased likelihood of significant brain lesions with age has been identifiedin neurologically normal dogs with epileptic seizures, the underlyingaetiology of epileptic seizures in
Gutierrez-Quintana, Rodrigo, Raimondi, Francesca, Sanchez-Masian, Daniel, Shihab, Nadia, Smith, Alex, Smith, Pete, Trevail, Raquel   +6 more
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Nuclear Envelope, Nuclear Lamina, and Inherited Disease [PDF]

, 2005
The nuclear envelope is composed of the nuclear membranes, nuclear lamina, and nuclear pore complexes. In recent years, mutations in nuclear-envelope proteins have been shown to cause a surprisingly wide array of inherited diseases.
Courvalin, Jean-Claude, Worman, Howard,
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A morphological and molecular approach to investigating infectious disease in early medieval Iberia: The necropolis of La Olmeda (Palencia, Spain)

American Journal of Biological Anthropology, Volume 185, Issue 1, September 2024.
Abstract Objective Here we investigate infectious diseases that potentially contribute to osteological lesions in individuals from the early medieval necropolis of La Olmeda (6th‐11th c. CE) in North Iberia. Materials and methods We studied a minimum number of 268 individuals (33 adult females; 38 adult males, 77 unknown/indeterminate sex; and 120 non ...
L. Coppola Bove, C. L. Kirkpatrick, A. Vigil‐Escalera Guirado, M. C. Botella López, K. I. Bos   +4 more
wiley   +1 more source

BMQ [PDF]

, 1963
BMQ: Boston Medical Quarterly was published from 1950-1966 by the Boston University School of Medicine and the Massachusetts Memorial ...
Antuna, Juan, Bagnoli, Thomas, Barber, Doris E., Cocchiarella, John P., Duke, Martin, Estes, J. Worth, Friedlander, Walter J., Goldsmith, Harry S., Gooding, Gretchen W., Goofman, Max L., Haseotes, Hytho V., Hass, Gerald, Hastings, A. Baird, Jackson, David R., Johnson, David S., Kechejian, Sarkis J., Kramer, Philip, Litman, George I., Madoff, Irving M., McLellan, Patricia A., O'Hara, Vincent S., Peabody, C. Newton, Pryles, Charles V., Small, Donald M., Tedeschi, Luke G., Walker, Sydney, III   +25 more
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Heritable and acquired disorders of phosphate metabolism: Etiologies involving FGF23 and current therapeutics [PDF]

, 2017
Phosphate is critical for many cellular processes and structural functions, including as a key molecule for nucleic acid synthesis and energy metabolism, as well as hydroxyapatite formation in bone.
Clickenbeard, Erica L., White, Kenneth E.   +1 more
core   +2 more sources

Metabolic profiling of psoriasis vulgaris and palmoplantar pustulosis

Experimental Dermatology, Volume 33, Issue 8, August 2024.
Abstract Psoriasis is a chronic inflammatory skin disorder with various subtypes, including psoriasis vulgaris (PV) and palmoplantar pustulosis (PPP). Metabolomics studies have provided insights into psoriasis pathogenesis. However, research on metabolomic alterations in PV and PPP patients is limited.
Yujin Lee, Seong Rae Kim, Mu Seong Ban, Howard Lee, Joo‐Youn Cho, Seong Jin Jo   +5 more
wiley   +1 more source

Phenotypic and Genotypic Characterization and Treatment of a Cohort with Familial Tumoral Calcinosis/Hyperostosis-Hyperphosphatemia Syndrome [PDF]

, 2016
Familial tumoral calcinosis (FTC)/hyperostosis-hyperphosphatemia syndrome (HHS) is a rare disorder caused by mutations in the genes encoding fibroblast growth factor-23 (FGF23), N-acetylgalactosaminyltransferase 3 (GALNT3), or KLOTHO.
Arabshahi, Bita, Brillante, Beth A., Chen, Marcus Y., Collins, Michael T., Del Rivero, Jaydira, Econs, Michael J., Gafni, Rachel I., Goldbach-Mansky, Raphaela, Gourh, Pravitt, Guthrie, Lori C., Hatab, Sarah, Heller, Theo, Ichikawa, Shoji, Jackson, Malaka B., McCarthy, Edward, Molinolo, Alfredo, Ramnitz, Mary Scott, Seo-Mayer, Patricia, White, Kenneth, Wodajo, Felasfa   +19 more
core   +1 more source