Results 1 to 10 of about 707,017 (165)

Acquired Antibiotic Resistance

Journal of Experimental and Molecular Biology, 2022
Antibiotics are chemicals used to control bacterial infections, produced by microorganisms (fungi, some bacteria) or obtained synthetically or semi-synthetically. The discovery of antibiotics has revolutionized the medical system, reducing morbidity and
Honceriu Iasmina
doaj   +2 more sources

Acquired resistance to first-line immune checkpoint inhibitors in esophageal squamous cell carcinoma: progression patterns and prognostic implications [PDF]

Frontiers in Immunology
BackgroundDespite the survival benefit of first-line immune checkpoint inhibitor (ICI)-based therapy in advanced esophageal squamous cell carcinoma (ESCC), acquired resistance (AR) remains a major clinical challenge, and its progression patterns and ...
Rui-Ying Zhang, Rui-Ying Zhang, Rui-Ying Zhang, Han Wu, Pei-Xiang Hao, Lu-Lu Guan, Dao Xin, Feng Wang, Feng Wang, Feng Wang   +9 more
doaj   +2 more sources

Targeting YAP to overcome acquired resistance to ALK inhibitors in ALK‐rearranged lung cancer

EMBO Molecular Medicine, 2019
Clinical benefit of ALK tyrosine kinase inhibitors (ALK‐TKIs) in ALK‐rearranged lung cancer has been limited by the inevitable development of acquired resistance, and bypass‐molecular resistance mechanisms remain poorly understood.
Mi Ran Yun, Hun Mi Choi, You Won Lee, Hyeong Seok Joo, Chae Won Park, Jae Woo Choi, Dong Hwi Kim, Han Na Kang, Kyoung‐Ho Pyo, Eun Joo Shin, Hyo Sup Shim, Ross A Soo, James Chih‐Hsin Yang, Sung Sook Lee, Hyun Chang, Min Hwan Kim, Min Hee Hong, Hye Ryun Kim, Byoung Chul Cho   +18 more
doaj   +2 more sources

Acquired Resistance to Antituberculosis Drugs

Emerging Infectious Diseases, 2018
Htin Lin Aung, Wint Wint Nyunt, Yang Fong, Bruce Russell, Gregory M. Cook, Si Thu Aung   +5 more
doaj   +4 more sources

Wine Yeast Cells Acquire Resistance to Severe Ethanol Stress and Suppress Insoluble Protein Accumulation during Alcoholic Fermentation

Microbiology Spectrum, 2022
Under laboratory conditions, acute 10% (vol/vol) ethanol stress causes protein denaturation and accumulation of insoluble proteins in yeast cells. However, yeast cells can acquire resistance to severe ethanol stress by pretreatment with mild ethanol ...
Masashi Yoshida, Noboru Furutani, Futsuki Imai, Takeo Miki, Shingo Izawa   +4 more
doaj   +1 more source

Case report: Durable response to alectinib in ALK-rearranged lung adenocarcinoma with acquired, crizotinib-resistant ALK C1156F mutation

Frontiers in Oncology, 2022
Treatment of ALK-rearranged non-small cell lung cancer (NSCLC) with tyrosine kinase inhibitors (TKIs) is challenged by the almost inevitable emergence of therapeutic resistance.
Chuangzhou Rao, Liangqin Nie, Xiaokang Wu, Xiaobo Miao, Ting Chen, Liuxi Chen, Dongqing Zhang, Quan Lin   +7 more
doaj   +1 more source

Systemic Acquired Resistance [PDF]

Plant Physiology, 1994
In the spectrum of plant-microbe interactions disease is a rare outcome. In many interactions complex, integrated defense mechanisms prevent infection and disease. These defensive systems include preformed physical and chemical barriers as well as inducible defenses such as the strengthening of cell walls or synthesis of antimicrobial compounds (i.e ...
J., Ryals, S., Uknes, E., Ward
openaire   +2 more sources

The Influencing Factors of Bacterial Resistance Related to Livestock Farm: Sources and Mechanisms

Frontiers in Animal Science, 2021
Bacterial resistance is a complex scientific issue. To manage this issue, we need to deeply understand the influencing factors and mechanisms. Based on the background of livestock husbandry, this paper reviews the factors that affect the acquisition of ...
Kaixuan Guo, Kaixuan Guo, Yue Zhao, Yue Zhao, Luqing Cui, Luqing Cui, Zhengzheng Cao, Zhengzheng Cao, Fan Zhang, Fan Zhang, Xiangru Wang, Jiawei Feng, Jiawei Feng, Menghong Dai, Menghong Dai   +14 more
doaj   +1 more source

Acquired Resistance in Arabidopsis [PDF]

The Plant Cell, 1992
Acquired resistance is an important component of the complex disease resistance mechanism in plants, which can result from either pathogen infection or treatment with synthetic, resistance-inducing compounds. In this study, Arabidopsis, a tractable genetic system, is shown to develop resistance to a bacterial and a fungal pathogen following 2,6 ...
S, Uknes, B, Mauch-Mani, M, Moyer, S, Potter, S, Williams, S, Dincher, D, Chandler, A, Slusarenko, E, Ward, J, Ryals   +9 more
openaire   +3 more sources

Immunobiology of Acquired Resistance to Ticks [PDF]

Frontiers in Immunology, 2020
Ticks are blood-sucking arthropods of great importance in the medical and veterinary fields worldwide. They are considered second only to mosquitos as vectors of pathogenic microorganisms that can cause serious infectious disorders, such as Lyme borreliosis and tick-borne encephalitis.
Hajime Karasuyama, Kensuke Miyake, Soichiro Yoshikawa   +2 more
openaire   +3 more sources