Results 71 to 80 of about 664 (168)

Synthesis, Structural Modification, and Bioactivity Evaluation of Substituted Acridones as Potent Microtubule Affinity-Regulating Kinase 4 Inhibitors. [PDF]

ACS Pharmacol Transl Sci, 2023
Voura M, Anwar S, Sigala I, Parasidou E, Fragoulidou S, Hassan MI, Sarli V.   +6 more
europepmc   +1 more source

Studies in the Cyclohexane Series. Part XIII. : Synthesis of Some Substituted 1,2,3,4-Tetrahydro-acridones and phenanthridones and N-Aryl-5-methyl 2,3,4,5,6,7- hexahydroindol-2-ones

, 1975
Department of Chemistry, University of Delhi, Delhi-110007 Manuscript received 28 November 1974; revised 2 April 1975; accepted 29 April 1975 Ethyl 4-methyleyclohexan-1-one-2-carboxylate is condensed with a number of primary aromatic amines at room ...
R. D. DESAI, H. S. BAJAJ, G. S. SAHARIA
core   +1 more source

Structure-activity relationships of Toxoplasma gondii cytochrome bc₁ inhibitors. [PDF]

Expert Opin Drug Discov, 2022
Alday PH, Nilsen A, Doggett JS.
europepmc   +1 more source

Synthesis of Fluorinated Benzophenones, Xanthones, Acridones, and Thioxanthones by Iterative Nucleophilic Aromatic Substitution

, 2016
Fluorination of fluorophores can substantially enhance their photostability and improve spectroscopic properties. To facilitate access to fluorinated fluorophores, bis­(2,4,5-trifluorophenyl)­methanone was synthesized by treatment of 2,4,5 ...
Blake R. Peterson (120721), Zachary R. Woydziak (1314633), Liqiang Fu (1792216)   +2 more
core   +1 more source

Acridone studies. XIII. The nature of hexabromoacridone

, 1975
Acheson's ?hexabromoacridone?1 is shown to be 1,2,3,4,5,7-hexabromo-9- acridone by a combination of N.M.R. spectroscopy and synthesis from specifically tritiated 9-acridones. In boiling piperidine, the bromines at C 1 and C 3 are replaced.
RH Prager
core   +1 more source

Discovery of dual function acridones as a new antimalarial chemotype

, 2009
Preventing and delaying the emergence of drug resistance is an essential goal of antimalarial drug development. Monotherapy and highly mutable drug targets have each facilitated resistance, and both are undesirable in effective long-term strategies ...
Martin J. Smilkstein, Sergio Wittlin, Aaron Janowsky, Rozalia A. Dodean, Hinrichs, D. J., Robert A. Johnson, Brun, R., Rolf Winter, Smilkstein, M. J., Jane X. Kelly, Cooper, R. A., Janowsky, A., Riscoe, M. K., David J. Hinrichs, Kristin D. Lane, Michael K. Riscoe, Winter, R., Reto Brun, Kelly, J. X., Johnson, R. A., Roland A. Cooper, Wittlin, S., Lane, K. D., Dodean, R. A.   +23 more
core   +1 more source

Synthesis and Anti-BVDV Activity of Acridones As New Potential Antiviral Agents

, 2016
In this study we report the design, synthesis, and activity against bovine viral diarrhea virus (BVDV) of a novel series of acridone derivatives. BVDV is responsible for major losses in cattle.
Jef Rozenski (57476), Bruno Canard (219785), Violetta Cecchetti (1316763), Erik De Clercq (55639), Oriana Tabarrini (1316745), Stefano Sabatini (1316760), Arnaldo Fravolini (2238265), Giuseppe Manfroni (1316766), Hélène Dutartre (119499), Johan Neyts (55640), Jan Paeshuyse (239006)   +10 more
core   +1 more source

Synthesis and anti-BVDV activity of acridones as new potential antiviral agents

, 2006
In this study we report the design, synthesis, and activity against bovine viral diarrhea virus (BVDV) of a novel series of acridone derivatives. BVDV is responsible for major losses in cattle.
Manfroni, Giuseppe, Cecchetti, Violetta, Sabatini, Stefano, De Clercq, Erik, Neyts, Johan, Tabarrini, Oriana, Dutartre, Hélène, Paeshuyse, Jan, Canard, Bruno, Rozenski, Jef, Fravolini, Arnaldo   +10 more
core   +1 more source

Acridone alkaloids

The Alkaloids: Chemistry and Biology, 2000
Skaltsounis, A.L., Mitaku, S., Tillequin, F.   +2 more
openaire   +2 more sources

Acridone Derivatives from Atalantia monophyla Inhibited Cancer Cell Proliferation through ERK Pathway. [PDF]

Molecules, 2022
Gao WY, Boonyarat C, Takomthong P, Plekratoke K, Hayakawa Y, Yenjai C, Kaewamatawong R, Chaiwiwatrakul S, Waiwut P.   +8 more
europepmc   +1 more source