Results 71 to 80 of about 601 (168)

Acridones As Antiviral Agents: Synthesis, Chemical and Biological Properties [PDF]

, 2013
Acridones are a class of compounds that have attracted attention in recent years for their wide range of biological properties, including selective inhibition of diverse human pathogenic viruses.
Damonte, Elsa Beatriz, Sepúlveda, Claudia Soledad, García, C. C., D'accorso, Norma Beatriz, Fascio, Mirta Liliana   +4 more
core   +1 more source

Synthesis of o‑(Dimethylamino)aryl Ketones, Acridones, Acridinium Salts, and 1H‑Indazoles by the Reaction of Hydrazones and Arynes

, 2016
A novel, efficient route to biologically and pharmaceutically important o-(dimethylamino)­aryl ketones, acridones, acridinium salts, and 1H-indazoles has been developed starting from readily available hydrazones of aldehydes and o-(trimethylsilyl)­aryl ...
Richard C. Larock (1353099), Anton V. Dubrovskiy (1972912)   +1 more
core   +1 more source

Synthesis of Fluorinated Benzophenones, Xanthones, Acridones, and Thioxanthones by Iterative Nucleophilic Aromatic Substitution [PDF]

, 2011
Fluorination of fluorophores can substantially enhance their photostability and improve spectroscopic properties. To facilitate access to fluorinated fluorophores, bis(2,4,5-trifluorophenyl)methanone was synthesized by treatment of 2,4,5 ...
Fu, Liqiang, Peterson, Blake R., Zachary R. Woydziak, Blake R. Peterson, Woydziak, Zachary R., Liqiang Fu   +5 more
core   +1 more source

Structure-activity relationships of Toxoplasma gondii cytochrome bc₁ inhibitors. [PDF]

Expert Opin Drug Discov, 2022
Alday PH, Nilsen A, Doggett JS.
europepmc   +1 more source

Palladium-Catalyzed Dual C–H Carbonylation of Diarylamines Leading to Diversified Acridones under CO-Free Conditions

A Pd-catalyzed dual C–H carbonylation of commercially available diarylamines using Co2(CO)8 as a safe CO source has been developed. This methodology provides a facile approach for the synthesis of diversified acridones in moderate to good yields.
Wenting Guo (800486), Jiali Huang (590640), Hualan Zhou (2828927), Chuanzhou Tao (16623916), Fujun Yin (1665427), Huiyan Wang (350287), Wenting Wu (174490), Weiming Hu (257720)   +7 more
core   +1 more source

Discovery of dual function acridones as a new antimalarial chemotype

, 2009
Preventing and delaying the emergence of drug resistance is an essential goal of antimalarial drug development. Monotherapy and highly mutable drug targets have each facilitated resistance, and both are undesirable in effective long-term strategies ...
Martin J. Smilkstein, Sergio Wittlin, Aaron Janowsky, Rozalia A. Dodean, Hinrichs, D. J., Robert A. Johnson, Brun, R., Rolf Winter, Smilkstein, M. J., Jane X. Kelly, Cooper, R. A., Janowsky, A., Riscoe, M. K., David J. Hinrichs, Kristin D. Lane, Michael K. Riscoe, Winter, R., Reto Brun, Kelly, J. X., Johnson, R. A., Roland A. Cooper, Wittlin, S., Lane, K. D., Dodean, R. A.   +23 more
core   +1 more source

Synthesis of Fluorinated Benzophenones, Xanthones, Acridones, and Thioxanthones by Iterative Nucleophilic Aromatic Substitution

, 2016
Fluorination of fluorophores can substantially enhance their photostability and improve spectroscopic properties. To facilitate access to fluorinated fluorophores, bis­(2,4,5-trifluorophenyl)­methanone was synthesized by treatment of 2,4,5 ...
Blake R. Peterson (120721), Zachary R. Woydziak (1314633), Liqiang Fu (1792216)   +2 more
core   +1 more source

Synthesis of pyrido[3,2-a] and indolo- [2,3-a]acridones

, 1999
1118-1120A new and convenient synthesis of pyrido[3,2-a]acridones 3 and indolo[2,3-a]acridones 5 starting from 4-hydroxy-2- methylquinoline 1 based on photochcmical approach is reported.
Selvi, S Thamarai, Mohan, P S
core  

Studies in the Cyclohexane Series. Part XIII. : Synthesis of Some Substituted 1,2,3,4-Tetrahydro-acridones and phenanthridones and N-Aryl-5-methyl 2,3,4,5,6,7- hexahydroindol-2-ones

, 1975
Department of Chemistry, University of Delhi, Delhi-110007 Manuscript received 28 November 1974; revised 2 April 1975; accepted 29 April 1975 Ethyl 4-methyleyclohexan-1-one-2-carboxylate is condensed with a number of primary aromatic amines at room ...
R. D. DESAI, H. S. BAJAJ, G. S. SAHARIA
core   +1 more source

Acridone Derivatives from Atalantia monophyla Inhibited Cancer Cell Proliferation through ERK Pathway. [PDF]

Molecules, 2022
Gao WY, Boonyarat C, Takomthong P, Plekratoke K, Hayakawa Y, Yenjai C, Kaewamatawong R, Chaiwiwatrakul S, Waiwut P.   +8 more
europepmc   +1 more source