Results 111 to 120 of about 23,326 (220)
Expression of microRNA related to bone remodeling regulation in plasma in patients with acromegaly
Backgraund. MiсroRNA are small regulatory factors that regulate gene expression by post-transcriptional regulation of mRNA, playing an important role in numerous cellular processes including organogenesis, apoptosis, cell proliferation and ...
Tatiana A. Grebennikova +6 more
doaj +1 more source
Acromegaly is the condition most often associated with an anterior pituitary tumour, which results from growth hormone and insulin-like growth factor 1 (IGF-1) excess.
John A. H. Wass +2 more
core +1 more source
BACKGROUND: Acromegaly is a severe neuroendocrine disorder caused by growth hormone hypersecretion, leading to various organ-system complications. In acromegaly, radiographic signs of osteoarthritis (OA) involving multiple joints develop even before the ...
M. A. Perepelova +9 more
doaj +1 more source
Prevalence of neoplasms in patients with acromegaly – the need for a national registry [PDF]
Introduction Acromegaly is an endocrine disorder caused predominantly by pituitary adenoma leading to autonomic oversecretion of growth hormone and secondary elevation of insulin-like growth factor 1 (IGF-1).
Jolanta Kowalczyk-Bołtuć +9 more
core +1 more source
Is there a Possibility of Early Diagnosis of Acromegaly by General Practicioner?
Introduction, Aim: Acromegaly is a disease that importantly shortens the life-expectancy without its treatment. Due to the slow and indolent clinical course of acromegaly, the diagnosis is often delayed, making the treatment less successful.
L. Atanasová, R. Slezák, J. Horáček
core +1 more source
Respiratory Dysfunctions in Acromegaly. Acromegaly and Sleep Apnea
Introduction: Acromegaly refers to an abnormal growth of some bones and tissues due to excessive action of insulin-like growth factor-1 (IGF-1). It occurs after the growth plate cartilage fuses in adulthood.
Velieva, Mukates +4 more
core +1 more source
Changes in retinal microvasculature and serum Gremlin-1 levels in acromegaly: A case-control study
Objective: There are controversial results about the effects of GH/IGF-1 on retinal vasculature. Gremlin-1 has roles in both pituitary tumorigenesis and angiogenesis.
Gokcen Unal Kocabas +10 more
doaj +1 more source
Pasireotide: a novel treatment for patients with acromegaly
Daniel Cuevas-Ramos,1 Maria Fleseriu2,3 1Department of Endocrinology and Metabolism, Neuroendocrinology Clinic, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico; 2Department of Medicine ...
Cuevas-Ramos D, Fleseriu M
core
Evaluation of Retinal Layers by Optical Coherence Tomography in Patients with Acromegaly
Objectives: Acromegaly, a rare endocrine disorder caused primarily by growth hormone (GH) secreting pituitary adenomas, leads to elevated levels of growth GH and insulin-like growth factor 1 (IGF-1), resulting in systemic complications and ocular ...
ogmen, berna evranos +11 more
core +1 more source

