Results 111 to 120 of about 24,454 (211)

[What is the value of determining immunoreactive GHRH in acromegaly?]

open access: yes, 1999
Acromegaly is usually due to autonomous, excessive secretion of growth hormone from a pituitary adenoma. One would expect growth hormone-releasing factor (GHRH) in these patients to be suppressed.
Bürgi, U   +3 more
core  

Changes in retinal microvasculature and serum Gremlin-1 levels in acromegaly: A case-control study

open access: yesPhotodiagnosis and Photodynamic Therapy
Objective: There are controversial results about the effects of GH/IGF-1 on retinal vasculature. Gremlin-1 has roles in both pituitary tumorigenesis and angiogenesis.
Gokcen Unal Kocabas   +10 more
doaj   +1 more source

Acromegaly - Pathology, diagnosis and treatment

open access: yes, 2005
This book reviews the pathophysiology and physical manifestations of acromegaly and discusses the multiple treatment options now available for the management of the patient with acromegaly.
Lamberts, S. W.   +4 more
core   +1 more source

Extraocular Muscle Enlargement in Acromegaly

open access: yes, 2022
Acromegaly is a disorder resulting from the hypersecretion of growth hormone (GH), usually by a pituitary adenoma. Ophthalmic manifestations can include visual field defects, cranial nerve palsies, and extraocular muscle (EOM) enlargement.
Alaa Bou Ghannam; Dalia El Hadi; Hala Mostafa; Hana Mansour; Ibrahim Hashim; Soubhi Tahhan; Tharwat Al Zahran
core  

Three-Dimensional Speckle-Tracking Echocardiography-Derived Tricuspid Annular Properties in Acromegaly—Results from the MAGYAR-Path Study

open access: yesBiomedicines
Introduction. Acromegaly is an endocrine pathology characterized by the overproduction of human growth hormone. The present study aimed to analyze three-dimensional speckle-tracking echocardiography (3DSTE)-derived tricuspid annular (TA) properties in ...
Attila Nemes   +6 more
doaj   +1 more source

Serial follow-up of presurgical treatment using pasireotide long-acting release with or without octreotide long-acting release for naive active acromegaly

open access: yes, 2017
The aim of the present study was to evaluate the serial changes of GH and IGF-1 in seven patients with naive, active acromegaly following presurgical treatment of the somatostatin analog pasireotide long-acting release (LAR) and octreotide LAR.
Chang, Jan-Shun;Tseng, Ham-Min;Chang, Tien-Chun   +1 more
core   +1 more source

Acromegaly and Heart Failure

open access: yes, 2019
In patients with acromegaly, chronic GH and IGF-I excess commonly causes a specific cardiomyopathy characterized by a concentric cardiac hypertrophy associated with diastolic dysfunction and, in later stages, with systolic dysfunction ending in heart ...
Colao A.   +3 more
core   +1 more source

Cardiovascular complications in acromegaly

open access: yes, 2004
Cardiovascular morbidity and mortality are increased in acromegaly. In fact, GH and IGF-I excess induces a specific cardiomyopathy. The early stage of acromegaly is characterized by the hyperkinetic syndrome (high heart rate and increased systolic output)
R. Pivonello   +6 more
core   +1 more source

Anxiety, depression and acromegaly: a systematic review

open access: yes
Purpose: scientific literature highlights risk factors linked to the onset of psychopathology in different medical pathological contexts. Acromegaly is a rare condition, particularly noteworthy due to the associated clinical psychological features.
Schwarz, Peter   +8 more
core   +1 more source

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