Results 111 to 120 of about 24,454 (211)
[What is the value of determining immunoreactive GHRH in acromegaly?]
Acromegaly is usually due to autonomous, excessive secretion of growth hormone from a pituitary adenoma. One would expect growth hormone-releasing factor (GHRH) in these patients to be suppressed.
Bürgi, U +3 more
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Changes in retinal microvasculature and serum Gremlin-1 levels in acromegaly: A case-control study
Objective: There are controversial results about the effects of GH/IGF-1 on retinal vasculature. Gremlin-1 has roles in both pituitary tumorigenesis and angiogenesis.
Gokcen Unal Kocabas +10 more
doaj +1 more source
Acromegaly - Pathology, diagnosis and treatment
This book reviews the pathophysiology and physical manifestations of acromegaly and discusses the multiple treatment options now available for the management of the patient with acromegaly.
Lamberts, S. W. +4 more
core +1 more source
Extraocular Muscle Enlargement in Acromegaly
Acromegaly is a disorder resulting from the hypersecretion of growth hormone (GH), usually by a pituitary adenoma. Ophthalmic manifestations can include visual field defects, cranial nerve palsies, and extraocular muscle (EOM) enlargement.
Alaa Bou Ghannam; Dalia El Hadi; Hala Mostafa; Hana Mansour; Ibrahim Hashim; Soubhi Tahhan; Tharwat Al Zahran
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Introduction. Acromegaly is an endocrine pathology characterized by the overproduction of human growth hormone. The present study aimed to analyze three-dimensional speckle-tracking echocardiography (3DSTE)-derived tricuspid annular (TA) properties in ...
Attila Nemes +6 more
doaj +1 more source
The aim of the present study was to evaluate the serial changes of GH and IGF-1 in seven patients with naive, active acromegaly following presurgical treatment of the somatostatin analog pasireotide long-acting release (LAR) and octreotide LAR.
Chang, Jan-Shun;Tseng, Ham-Min;Chang, Tien-Chun +1 more
core +1 more source
In patients with acromegaly, chronic GH and IGF-I excess commonly causes a specific cardiomyopathy characterized by a concentric cardiac hypertrophy associated with diastolic dysfunction and, in later stages, with systolic dysfunction ending in heart ...
Colao A. +3 more
core +1 more source
Cardiovascular complications in acromegaly
Cardiovascular morbidity and mortality are increased in acromegaly. In fact, GH and IGF-I excess induces a specific cardiomyopathy. The early stage of acromegaly is characterized by the hyperkinetic syndrome (high heart rate and increased systolic output)
R. Pivonello +6 more
core +1 more source
Anxiety, depression and acromegaly: a systematic review
Purpose: scientific literature highlights risk factors linked to the onset of psychopathology in different medical pathological contexts. Acromegaly is a rare condition, particularly noteworthy due to the associated clinical psychological features.
Schwarz, Peter +8 more
core +1 more source

