Results 101 to 110 of about 20,619 (221)
Acromegaly is a rare, slowly progressive disease caused by chronic hypersecretion of growth hormone (GH) and excess circulating insulin-like growth factor-1 (IGF-1).
Deepali Lodha +3 more
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Expression of microRNA related to bone remodeling regulation in plasma in patients with acromegaly
Backgraund. MiсroRNA are small regulatory factors that regulate gene expression by post-transcriptional regulation of mRNA, playing an important role in numerous cellular processes including organogenesis, apoptosis, cell proliferation and ...
Tatiana A. Grebennikova +6 more
doaj +1 more source
Is there a Possibility of Early Diagnosis of Acromegaly by General Practicioner?
Introduction, Aim: Acromegaly is a disease that importantly shortens the life-expectancy without its treatment. Due to the slow and indolent clinical course of acromegaly, the diagnosis is often delayed, making the treatment less successful.
L. Atanasová, R. Slezák, J. Horáček
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BACKGROUND: Acromegaly is a severe neuroendocrine disorder caused by growth hormone hypersecretion, leading to various organ-system complications. In acromegaly, radiographic signs of osteoarthritis (OA) involving multiple joints develop even before the ...
M. A. Perepelova +9 more
doaj +1 more source
Changes in retinal microvasculature and serum Gremlin-1 levels in acromegaly: A case-control study
Objective: There are controversial results about the effects of GH/IGF-1 on retinal vasculature. Gremlin-1 has roles in both pituitary tumorigenesis and angiogenesis.
Gokcen Unal Kocabas +10 more
doaj +1 more source
A case of acromegaly complicated with diabetic ketoacidosis, pituitary apoplexy, and lymphoma
Acromegaly is always complicated with comorbidities and increased mortality. The disease activity and mortality outcomes are highly correlated to the level of growth hormone and insulin-like growth factor 1.
He-Jiun Jiang +2 more
doaj +1 more source
Prevalence of neoplasms in patients with acromegaly – the need for a national registry
Introduction Acromegaly is an endocrine disorder caused predominantly by pituitary adenoma leading to autonomic oversecretion of growth hormone and secondary elevation of insulin-like growth factor 1 (IGF-1).
Jolanta Kowalczyk-Bołtuć +9 more
core +1 more source
Introduction. Acromegaly is an endocrine pathology characterized by the overproduction of human growth hormone. The present study aimed to analyze three-dimensional speckle-tracking echocardiography (3DSTE)-derived tricuspid annular (TA) properties in ...
Attila Nemes +6 more
doaj +1 more source
Pasireotide: a novel treatment for patients with acromegaly
Daniel Cuevas-Ramos,1 Maria Fleseriu2,3 1Department of Endocrinology and Metabolism, Neuroendocrinology Clinic, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico; 2Department of Medicine ...
Cuevas-Ramos D, Fleseriu M
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