Results 81 to 90 of about 49,296 (268)
Investigation of Survivin Promoter-31 G/C Polymorphism and Survivin Levels in Acromegaly
Endocrinology Research and Practice, 2021 Objevtive: Acromegaly is a rare disease characterized by growth hormone hypersecretion generally arising from pituitary adenomas. Survivin, an apoptosis inhibitor protein, plays an important role in cell cycle regulation and possibly involves hypophysis ...
Muzaffer İLHAN +7 more
doaj +1 more source
Risk for acromegaly-related comorbidities by sex in Korean acromegaly.
Journal of Clinical Endocrinology and Metabolism, 2020 CONTEXT Reports on the incidence, characteristics, and comorbidity in Asian patients with acromegaly are scarce. OBJECTIVE To evaluate the incidence of acromegaly and risk of comorbidities in East Asia, especially South Korea.
K. Park, Eun Jig Lee, G. Seo, C. Ku
semanticscholar +1 more source
Risk Management and Insurance Review, EarlyView.Abstract This study examines whether underwriting methods—representation, medical examination, extra premiums, and coverage—effectively mitigate adverse selection using data from an insurance company. Regarding representation, we focus on statements disclosing pre‐existing medical conditions.
Chia‐Ling Ho +3 more
wiley +1 more source
Topics in Companion Animal Medicine, 2012 Acromegaly, or hypersomatotropism, results from chronic, excessive secretion of growth hormone in the adult animal. The anabolic effects of growth hormone are exerted through the intermediary hormone, insulin-like growth factor 1, which is produced in the liver under the influence of growth hormone.
openaire +2 more sources
Unexplained massive pulmonary embolism in acromegaly patient: A case report
Clinical Case ReportsKey Clinical Message Our case highlights the importance of recognizing acromegaly as a potential risk factor for venous thromboembolism (VTE). Despite a thorough thrombophilia workup yielding unremarkable results, further research is warranted to ...
Usamah Al‐Anbagi +3 more
doaj +1 more source
Prevalence of acromegaly in patients with symptoms of sleep apnea.
PLoS ONE, 2017 Acromegaly is a rare disease with nonspecific symptoms with acral enlargement being almost universally present at diagnosis. The estimated prevalence is 40-125 cases/million but targeted universal screening studies have found a higher prevalence (about ...
Gemma Sesmilo +14 more
doaj +1 more source
Octreotide Counteracts IFN‐γ‐Induced Endothelial Inflammation
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 5, May 2026.ABSTRACT Endothelial cells maintain vascular homeostasis through the regulation of permeability and coagulation. Interferon‐gamma (IFN‐γ), a proinflammatory cytokine released by activated T lymphocytes and natural killer cells, disrupts endothelial junctional integrity, leading to barrier dysfunction.
Saikat Fakir +3 more
wiley +1 more source
Automatic Detection for Acromegaly Using Hand Photographs: A Deep-Learning Approach
IEEE Access, 2021 Machine learning assisted diagnosis of acromegaly from facial photographs has been proved feasible in recent years. According to our previous research, facial and limb changes exist in patients with acromegaly at early stage.
Chengbin Duan +9 more
doaj +1 more source
TRH: Pathophysiologic and clinical implications [PDF]
, 1985 Thyrotropin releasing hormone is thought to be a tonic stimulator of the pituitary TSH secretion regulating the setpoint of the thyrotrophs to the suppressive effect of thyroid hormones. The peptide stimulates the release of normal and elevated prolactin.
A. Enjalbert +82 more
core +1 more source
Journal of Clinical Endocrinology and Metabolism, 2020 PURPOSE Osteopathy is an emerging complication of acromegaly. In somatostatin receptor ligands (SRL)-resistant patients, Pegvisomant (PegV) and Pasireotide LAR (Pasi) are used for acromegaly treatment, but their effect on skeletal health is still not ...
S. Chiloiro +10 more
semanticscholar +1 more source