Results 81 to 90 of about 23,326 (220)

Clinical and economic burden among older adults with acromegaly in the United States

Journal of Comparative Effectiveness Research
Aim: To compare healthcare resource utilization (HCRU) and costs between older adults with and without acromegaly. Materials & methods: Using 2017–2022 100% Medicare Research Identifiable Files, we identified beneficiaries (≥65 years) with prevalent ...
Tiffany P Quock, Eunice Chang, Ashis K Das, Amanda Speller, Marian H Tarbox, Stacy K Rattana, Ingrid E Paulson, Michael S Broder   +7 more
doaj   +1 more source

Prevalence of acromegaly in patients with symptoms of sleep apnea.

PLoS ONE, 2017
Acromegaly is a rare disease with nonspecific symptoms with acral enlargement being almost universally present at diagnosis. The estimated prevalence is 40-125 cases/million but targeted universal screening studies have found a higher prevalence (about ...
Gemma Sesmilo, Eugenia Resmini, Marcel Sambo, Concepción Blanco, Fernando Calvo, Fernando Pazos, Pablo Fernández-Catalina, Purificación Martínez de Icaya, Concepción Páramo, Carmen Fajardo, Mónica Marazuela, Cristina Álvarez-Escolá, Juan Jose Díez, Verónica Perea, ACROSAHS study group   +14 more
doaj   +1 more source

Transcriptional Profiling of Growth Hormone–Secreting Pituitary Adenoma Stem‐Like Cells: Unveiling the Significant Role of CXCR4 in Tumorigenesis and Clinical Applications

MedComm, Volume 7, Issue 9, September 2026.
Growth hormone–secreting pituitary adenomas harbor hPASCs (human pituitary adenoma stem‐like cells). Genetic profiling of hPASCs identified CXCR4 as a significant gene orchestrating a regulatory network in the self‐renewal and differentiation of hPASCs, as well as the modulation of tumor cells and the microenvironment.
LinHao Yuan, Hao Yang, BaoWang Li, Huimin Sui, Peiliang Li, Xu Wang, Jiang Li, Guijun Jia, Zhaohui Zhu, Deling Li, Wang Jia, Peng Kang   +11 more
wiley   +1 more source

The Association Between Somatostatin Receptor Ligand and Vitamin B12 in Patients with Acromegaly

, 2022
Objective: Vitamin B12 deficiency causes hematologic and neuropsychiatric disorders, thus it is important to evaluate it in risky situations. In this study, we aimed to evaluate the association between somatostatin receptor ligands and vitamin B12 in ...
Tuğçe Eşkazan, EŞKAZAN, TUĞÇE, Emre Durcan, Ali İbrahim Hatemi, HATEMİ, ALİ İBRAHİM, KADIOĞLU, PINAR, Durcan, Emre, Yeliz Yagiz Ozogul, Yeliz Yağız Özoğul, Hande Mefküre Özkaya, Cem Sulu, ŞAHİN, Serdar, Ozogul, Yeliz Yagiz, Ebru Çiçek, ÇİÇEK, EBRU, Pinar Kadioglu, Serdar Şahin, SULU, CEM, Pınar Kadıoğlu, ÖZKAYA, HANDE MEFKURE   +19 more
core   +1 more source

Voice Quality in Individuals With Acquired Immunodeficiency Syndrome

International Journal of Language &Communication Disorders, Volume 61, Issue 5, September/October 2026.
ABSTRACT Background Speech and voice disorders are frequently observed in individuals with acquired immunodeficiency syndrome (AIDS). However, the literature lacks detailed descriptions of how perceptual and acoustic characteristics manifest in the voice quality profiles of this population.
Vanessa Medina, Andrea Baldi de Freitas, Luiz Carlos Rusilo, Jean Carlo Gorinchteyn, Zuleica Antônia Camargo   +4 more
wiley   +1 more source

Obstructive Sleep Apnea Syndrome in Acromegaly Before and After Treatment

, 2014
Introduction Obstructive sleep apnea syndrome (OSAS) prevalence in acromegaly patients is very common compared with general population. It is thought that OSAS in acromegaly patients evolve because of reversible and irreversible anatomical changes ...
Aksu, Murat, Cakir, Ilkay, Ilkay Çakir, Sevda Ismailogullari, Selda Korkmaz, Karaca, Zuleyha, Korkmaz, Selda, Züleyha Karaca, Murat Aksu, Bayram, Fahri, Fahri Bayram, Ismailogullari, Sevda   +11 more
core   +1 more source

Feline Acromegaly [PDF]

Topics in Companion Animal Medicine, 2012
Acromegaly, or hypersomatotropism, results from chronic, excessive secretion of growth hormone in the adult animal. The anabolic effects of growth hormone are exerted through the intermediary hormone, insulin-like growth factor 1, which is produced in the liver under the influence of growth hormone.
openaire   +2 more sources

Clinical and biochemical characteristics of patients with acromegaly and normal or increased prolactin levels

Alʹmanah Kliničeskoj Mediciny
Background: Prevalence of hyperprolactinemia in patients with acromegaly is 30 to 40%. Since recently, the necessity of screening for acromegaly in hyperprolactinemic patients with pituitary adenoma has been actively debated. The literature on this issue
Yuliya A. Kukushkina, Irena A. Ilovayskaya   +1 more
doaj   +1 more source

Diagnostic challenges and management of a patient with acromegaly due to ectopic growth hormone-releasing hormone secretion from a bronchial carcinoid tumour

Endocrinology, Diabetes & Metabolism Case Reports, 2017
A male patient presented at the age of 30 with classic clinical features of acromegaly and was found to have elevated growth hormone levels, not suppressing during an oral glucose tolerance test.
Nikolaos Kyriakakis, Jacqueline Trouillas, Mary N Dang, Julie Lynch, Paul Belchetz, Márta Korbonits, Robert D Murray   +6 more
doaj   +1 more source

Midlife Growth Hormone Receptor Ablation Extends Healthy Lifespan and Induces Sex‐Specific Hepatic Transcriptional Changes at Single‐Cell Resolution

Aging Cell, Volume 25, Issue 9, September 2026.
Reducing growth hormone receptor signaling beginning in middle age is sufficient to extend lifespan in both sexes while preserving metabolic and physical function, particularly in males. Single‐nucleus RNA sequencing reveals sex‐specific hepatic transcriptional remodeling associated with these longevity benefits. ABSTRACT Suppression of growth hormone (
Silvana Duran‐Ortiz, Edward O. List, Jonathan A. Young, Yuji Ikeno, Shouan Zhu, Todd McHugh, Patrick M. O'Connor, Minhoo Kim, Bérénice A. Benayoun, Fabian Benencia, Reetobrata Basu, Emmanuel A. Gotte, Darlene E. Berryman, John J. Kopchick   +13 more
wiley   +1 more source