Results 71 to 80 of about 24,454 (211)
Trends in Endocrinology & Metabolism, 1992 In the majority of cases, acromegaly is due to GH hypersecretion by a somatotroph pituitary tumor. The etiology of acromegaly is not known, and may be related to GHRH hypersecretion, intrinsic pituitary defect, or a combination thereof. Recent physiologic data and molecular biology techniques provide insights into the pathophysiology of this condition.
openaire +3 more sources
Differential Diagnosis Performance of ChatGPT in Oral and Maxillofacial Pathology
Oral Diseases, EarlyView.ABSTRACT Objective To evaluate ChatGPT (GPT‐5.1) for ranked differential diagnoses in oral and maxillofacial pathology, assess image effects on diagnostic performance and examine output stability across repeated runs. Methods This retrospective diagnostic accuracy study included 160 biopsy‐confirmed cases.
Sohaib Shujaat +6 more
wiley +1 more source
The Role of Comorbidities in Pyoderma Among Canine and Feline Diabetic Patients
Veterinary Dermatology, EarlyView.Background: Pyoderma is considered a secondary complication of diabetes mellitus (DM), yet the relationship remains unclear. One study found 22% of diabetic dogs with dermatopathy had no other comorbidities, whereas cats have not been evaluated.
Virginia Wixon +2 more
wiley +1 more source
Myelodysplastic Syndrome in an Acromegaly Patient: A Case Report
Endocrinology Research and Practice, 2005 Acromegaly patients have higher incidence of neoplasia than the general population, especially for colonic carcinoma. Recently, various hematological malignancies have been reported in patients with acromegaly.
Ramazan Sarı +5 more
doaj +2 more sources
Investigation of Survivin Promoter-31 G/C Polymorphism and Survivin Levels in Acromegaly
Endocrinology Research and Practice, 2021 Objevtive: Acromegaly is a rare disease characterized by growth hormone hypersecretion generally arising from pituitary adenomas. Survivin, an apoptosis inhibitor protein, plays an important role in cell cycle regulation and possibly involves hypophysis ...
Muzaffer İLHAN +7 more
doaj +1 more source
Alʹmanah Kliničeskoj MedicinyBackground: The incidence of cancer in acromegaly varies substantially, ranging from 6.8% to 21.3%. Population-based studies have revealed differences both in the tumor types and in the risk factors for cancer development in acromegaly. Aim: To assess
Natalia I. Borovskaya +5 more
doaj +1 more source
International Journal of Cancer, Volume 159, Issue 11, Page 2633-2652, 1 December 2026.ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari +10 more
wiley +1 more source
, 2011 Acromegaly is the condition most often associated with an anterior pituitary tumour, which results from growth hormone and insulin-like growth factor 1 (IGF-1) excess.
John A. H. Wass +2 more
core +1 more source
Prevalence of acromegaly in patients with symptoms of sleep apnea.
PLoS ONE, 2017 Acromegaly is a rare disease with nonspecific symptoms with acral enlargement being almost universally present at diagnosis. The estimated prevalence is 40-125 cases/million but targeted universal screening studies have found a higher prevalence (about ...
Gemma Sesmilo +14 more
doaj +1 more source
A Zebrafish Acromegaly Model Elevates DNA Damage and Impairs DNA Repair Pathways
Biology, 2018 Acromegaly is a pathological condition due to excess growth hormone (GH) secretion. Acromegaly patients exhibit a deterioration of health and many associated complications, such as cardiovascular issues, arthritis, kidney diseases, muscular weakness, and
Abdalla Elbialy +3 more
doaj +1 more source