Results 91 to 100 of about 24,454 (211)

Diagnostic challenges and management of a patient with acromegaly due to ectopic growth hormone-releasing hormone secretion from a bronchial carcinoid tumour

open access: yesEndocrinology, Diabetes & Metabolism Case Reports, 2017
A male patient presented at the age of 30 with classic clinical features of acromegaly and was found to have elevated growth hormone levels, not suppressing during an oral glucose tolerance test.
Nikolaos Kyriakakis   +6 more
doaj   +1 more source

Diffuse cranial vault hyperostosis associated with long‐term antiepileptic therapy: Autopsy findings and differential diagnostic considerations

open access: yesJournal of Forensic Sciences, Volume 71, Issue 6, Page 2981-2986, November 2026.
Abstract Diffuse cranial vault hyperostosis is an uncommon finding and may present a diagnostic challenge in clinical and forensic practice. We report the case of a 53‐year‐old woman with a long‐standing history of epilepsy treated with phenytoin and sodium valproate who collapsed at home suddenly and died despite resuscitative efforts.
Maria Piagkou   +7 more
wiley   +1 more source

ACROMEGALY. Case report

open access: yes, 2014
Acromegaly - a neuroendocrine pathology, caused by chronic overproduction of growth hormone. Chronic overproduction of somatotropin and insulin growth factor (IGF) is clinically expressed in gigantism or acromegaly.
E L Soyustova
core   +1 more source

Hypertriglyceridemia: Causes, Consequences, Diagnosis, and Management

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Hypertriglyceridemia (HTG) arises from the interplay between genetic susceptibility and secondary or precipitating factors, leading to dysregulated triglyceride‐rich lipoprotein (TRL) metabolism. Increased TRL production and impaired clearance promote distinct risk phenotypes: accumulation of apolipoprotein B(apoB)‐containing TRL remnants contributes ...
Shanshan Qi   +9 more
wiley   +1 more source

Hepatocyte Growth Hormone Receptor Ablation Is Associated With Aging Phenotypes and Hepatic Mitochondrial Dysfunction

open access: yesAging Cell, Volume 25, Issue 10, October 2026.
Hepatocyte‐specific GHR ablation is associated with hepatic and age‐related pathologies, triggering adipose‐liver crosstalk via elevated circulating GH and subsequent CD36‐dependent hepatic steatosis. This loss impairs STAT5b phosphorylation and enhances PPARγ nuclear activation, upregulating Pdk4 and Cd36 to drive mitochondrial dysfunction and ectopic
Kangkang Yang   +7 more
wiley   +1 more source

Assessment of Serum B-Arestin Level in Acromegaly Patients with Diabetes Mellitus

open access: yesDiyala Journal of Medicine
Background: Acromegaly is a rare endocrine disorder, with an annual incidence of 4 cases per million and a prevalence of 40 cases per million. The condition results from a pituitary adenoma that secretes growth hormone.
Hiba Ghassan Rajab   +2 more
doaj   +1 more source

Hip Structure Analyses in Acromegaly: Decrease of Cortical Bone Thickness After Treatment: A Longitudinal Cohort Study

open access: yesJBMR Plus, 2019
Long‐standing growth hormone (GH) excess causes the skeletal clinical signs of acromegaly with typical changes in bone geometry, including increased cortical bone thickness (CBT).
Kristin Godang   +8 more
doaj   +1 more source

IMPROVE 2025: The 3rd International Meeting on Pathway‐Related Obesity: Vision & Evidence

open access: yesClinical Obesity, Volume 16, Issue 5, October 2026.
ABSTRACT An international cohort of 161 clinicians and researchers from 19 countries attended the 3rd International Meeting on Pathway‐Related Obesity: Vision & Evidence (IMPROVE) in Prague, Czech Republic, on 2–4 July 2025. The aims of the meeting were to advance understanding of hyperphagia and obesity caused by defects in the melanocortin‐4 receptor
Jesús Argente   +17 more
wiley   +1 more source

Feline Acromegaly [PDF]

open access: yesTopics in Companion Animal Medicine, 2012
Acromegaly, or hypersomatotropism, results from chronic, excessive secretion of growth hormone in the adult animal. The anabolic effects of growth hormone are exerted through the intermediary hormone, insulin-like growth factor 1, which is produced in the liver under the influence of growth hormone.
openaire   +2 more sources

From gene regulation to membrane excitability: A new role for thyroid hormone in skeletal muscle

open access: yes
The Journal of Physiology, EarlyView.
Eric N. Jimenez‐Vazquez   +1 more
wiley   +1 more source

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