Results 61 to 70 of about 49,296 (268)

Acromegaly, inflammation and cardiovascular disease: a review

Reviews in Endocrine & Metabolic Disorders, 2020
Acromegaly is characterized by Growth Hormone (GH) and Insulin-like Growth Factor 1 (IGF-1) excess. Uncontrolled acromegaly is associated with a strongly increased risk of cardiovascular disease (CVD), and numerous cardiovascular risk factors remain ...
Thalijn L. C. Wolters, M. Netea, N. Riksen, A. Hermus, R. Netea-Maier   +4 more
semanticscholar   +1 more source

Acromegaly presenting with myelopathy due to ossification of posterior longitudinal ligament: a case report

BMC Musculoskeletal Disorders, 2021
Background Acromegaly is a rare disease caused by high serum levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1), often originating from a pituitary adenoma.
Daisuke Kamakura, Katsunori Fukutake, Kazumasa Nakamura, Shintaro Tsuge, Keiji Hasegawa, Naobumi Tochigi, Akihito Wada, Tetsuo Mikami, Hiroshi Takahashi   +8 more
doaj   +1 more source

Heat Intolerance and Hyperhidrosis as the only Presenting Manifestations of Acromegaly: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2020
Acromegaly is a state of Growth Hormone (GH) excess characterised by coarse facial features, acral enlargement, hyperhidrosis, headache, visual disturbances and visceromegaly. The most common cause of acromegaly is pituitary adenoma.
TN Kamalesh, HA VIJAYA SARATHY, NT SREEDEVI   +2 more
doaj   +1 more source

Standards of care for medical management of acromegaly in pituitary tumor centers of excellence (PTCOE)

Pituitary
A series of consensus guidelines on medical treatment of acromegaly have been produced in the last two decades. However, little information is available on their application in clinical practice.
Acromegaly · Octreotide, Cabergoline · Lanreotide, Pasireotide · Pegvisomant, A. Giustina, ·. M. M. Uygur, ·. S. Frara, ·. A. Barkan, N. Biermasz, ·. P. Chanson, P. Freda, M. Gadelha, L. Haberbosch, U. B. Kaiser, S. Lamberts, ·. E. Laws, L. Nachtigall, ·. V. Popovic, ·. M. Reincke, ·. A. J. V. D. Lely, J. Wass, ·. S. Melmed, F. Casanueva   +21 more
semanticscholar   +1 more source

Differential Tissue Response to Growth Hormone in Mice [PDF]

, 2018
Growth hormone (GH) has been shown to act directly on multiple tissues throughout the body. Historically, it was believed that GH acted directly in the liver and only indirectly in other tissues via insulin‐like growth hormone 1 (IGF‐1).
Banerjee, Ronadip R., Berry, Ryan, Frank, Stuart J., McGinnis, Graham R., Young, Martin E.   +4 more
core   +2 more sources

High Sensitivity Mass Spectrometric Quantification of Serum Growth Hormone by Amphiphilic Peptide Conjugation [PDF]

, 2012
Amphiphilic peptide conjugation affords a significant increase in sensitivity with protein quantification by electrospray-ionization mass spectrometry.
Arsene, Arsene, Barkan, Busch, Cech, Cech, Chai, Chanson, Foettinger, Frahm, Giustina, Halquist, Hofmann, Kulevich, Ligon, Litterscheid, Markkanen, Mirzaei, Shortreed, Shuford, Ullmer, Williams, Williams, Wu, Yang, Yang   +25 more
core   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Polycystic ovary syndrome preceding the diagnosis of acromegaly: a retrospective study in 97 reproductive-aged women

Reproductive Biology and Endocrinology, 2023
Background Acromegaly is a disease of growth hormone excess that results in enlargement of extremities, abnormal glucose and lipid metabolism, and gonadal disruption. Manifestations of the disease are insidious and typically lead to a diagnostic delay of
Anamil M. Khiyami, Tahereh Orouji Jokar, Hussein M. Abdallah, Paul A. Gardner, Georgios A. Zenonos, Aaron K. Styer, Pouneh K. Fazeli   +6 more
doaj   +1 more source

Clinical characteristics and efficacy of acromegaly treatment in the Udmurt Republic

Alʹmanah Kliničeskoj Mediciny, 2022
Background: Acromegaly is a severe neuroendocrine disorder caused by chronic overproduction of growth hormone and insulin-like growth factor 1 and associated with a variety of clinical manifestations, debilitating complications and progressive disability,
Guzel M. Nurullina, Guzyal I. Akhmadullina, Irina S. Maslova, Alexandra R. Nikolaeva   +3 more
doaj   +1 more source

Incidence of bronchiectasis in patients with acromegaly: a cohort study

Frontiers in Endocrinology
ObjectiveAssociations between acromegaly and several respiratory diseases, such as obstructive lung disease or sleep apnea, have been suggested, but the relationship between bronchiectasis and acromegaly is unclear.
Hyun-Il Gil, Kyungdo Han, Sangmo Hong, Cheol-Young Park   +3 more
doaj   +1 more source