Results 41 to 50 of about 20,619 (221)
Introduction: The vitamin D receptor (VDR) gene is one of the most widely studied tumorigenesis-related genes. The primary objective of this study was assessment of possible roles of VDR gene polymorphisms in acromegaly, with regard to the activity of ...
Aleksandra Jawiarczyk-Przybyłowska +5 more
doaj +1 more source
Walking Balance in Individuals with Acromegaly
Introduction: Acromegaly is characterized by growth hormone excess. It adversely affects the patients’ musculoskeletal and neural systems, consequently impairing physical function.
Wang, Yuqi
core
Screening colonoscopy tests in acromegaly patients – authors’ observations [PDF]
Background . The prevalence of adenomas which cause acromegaly is estimated at 50–70 mln people. They secrete excess of growth hormone and increase the risk of benign and malignant tumours.
Maria Kurowska +11 more
core +1 more source
Hypertension and Acromegaly [PDF]
Hypertension is one of the most frequent complications in acromegaly, with a median frequency of 33.6% (range, 11%-54.7%). Although the pathogenesis has not been fully elucidated, it probably results from concomitant factors leading to expansion of extracellular fluid volume, increase of peripheral vascular resistance, and development of sleep apnea ...
Soraya, Puglisi, Massimo, Terzolo
openaire +2 more sources
Serum Levels of Asprosin, a Novel Adipokine, Are Significantly Lowered in Patients with Acromegaly
Background. Asprosin is a novel identified adipokine secreted mainly by white adipose tissue, which is elevated in metabolic diseases such as diabetes and obesity.
Xiaoan Ke +8 more
doaj +1 more source
Background Acromegaly is a disease of growth hormone excess that results in enlargement of extremities, abnormal glucose and lipid metabolism, and gonadal disruption. Manifestations of the disease are insidious and typically lead to a diagnostic delay of
Anamil M. Khiyami +6 more
doaj +1 more source
Background Acromegaly is a rare endocrine disease caused by excessive growth hormone (GH) secretion typically due to a pituitary adenoma. Patients ineligible for or with an inadequate response to surgery and/or radiotherapy often require pharmacotherapy ...
Maxwell Koobatian +4 more
doaj +1 more source
Clinical characteristics and efficacy of acromegaly treatment in the Udmurt Republic
Background: Acromegaly is a severe neuroendocrine disorder caused by chronic overproduction of growth hormone and insulin-like growth factor 1 and associated with a variety of clinical manifestations, debilitating complications and progressive disability,
Guzel M. Nurullina +3 more
doaj +1 more source
Acromegaly with metastatic renal cell carcinoma: Lung, gluteal and scapular metastasis
The association between acromegaly and increased incidence of malignancy has been reported due to high GH and IGF levels. Although the incidence of all malignancies increases in patients with acromegaly, renal cell carcinoma (RCC) has been rarely ...
Ziynet Alphan Uc +3 more
doaj +1 more source
Guidelines for acromegaly management: An update
Objective: The Acromegaly Consensus Group reconvened in November 2007 to update guidelines for acromegaly management. Participants: The meeting participants comprised 68 pituitary specialists, including neurosurgeons and endocrinologists with extensive ...
Giustina A., Doglietto F.
core +1 more source

