Results 31 to 40 of about 49,296 (268)

Time spent with cats is never wasted: Lessons learned from feline acromegalic cardiomyopathy, a naturally occurring animal model of the human disease [PDF]

, 2018
BackgroundIn humans, acromegaly due to a pituitary somatotrophic adenoma is a recognized cause of increased left ventricular (LV) mass. Acromegalic cardiomyopathy is incompletely understood, and represents a major cause of morbidity and mortality.
A Colao, A Colao, A Colao, A Colao, A Colao, A Colao, A Colao, A Colao, A Mestron, A Piovesan, AC Dirtu, AM Pereira, B Posch, BJ Maron, BPP Meij, BR Bond, C Paige, C-Y Liu, CJL Little, CR Lamb, David B. Church, David J. Connolly, DJ Connolly, F Fracassi, G Jacobs, G Lombardi, G Lombardi, J Dal, J Gilbert, JA Myers, JK Sangster, JM Fletcher, JR Payne, JT Lie, Kieran Borgeat, LJ Wilkie, Lois Wilkie, M Galderisi, M Lesser, M Maxie Grant, M Nishiki, M Rosca, M-LL Jaffrain-Rea, MD Kittleson, ME Peterson, ME Peterson, NJ Pereira, Norelene Harrington, NS Moise, NS Moise, O Kershaw, OM Dekkers, P Menaut, PR Fox, PR Fox, PR Fox, PR Fox, PR Fox, R Baldelli, R Gostelow, R Pivonello, RC Weichselbaum, S Brown, S Fazio, S Fazio, S Fazio, S Fieffe, S Murarka, S Niessen, SJM Niessen, SJM Niessen, SJM Niessen, SK Liu, SK Liu, Stijn J. M. Niessen, SV Keyte, T Wagner, T. Rosol, Vincenzo Lionetti, Virginia Luis Fuentes, WL McGuffin   +80 more
core   +2 more sources

Prevalence of comorbidities and concomitant medication use in acromegaly: analysis of real-world data from the United States

Pituitary, 2022
Purpose Patients receiving treatment for acromegaly often experience significant associated comorbidities for which they are prescribed additional medications.
M. Fleseriu, A. Barkan, Maria del Pilar Schneider, Yannis Darhi, A. de Pierrefeu, A. Ribeiro-Oliveira, S. Petersenn, S. Neggers, S. Melmed   +8 more
semanticscholar   +1 more source

Acromegaly, Mr Punch and caricature. [PDF]

, 1996
The origin of Mr Punch from the Italian Pulcinella of the Commedia dell'arte is well known but his feature, large hooked nose, protruding chin, kyphosis and sternal protrusion all in an exaggerated form also suggest the caricature of an acromegalic. This
Armstrong R, Coues W P, Cruickshank G, David Bryson, De Souze-Leite J D, Dumas P, Ferrier D, Fritsche, Gourevitch D, Grossman A, Hutchinson W, Jewesbury R C, Levine D, Lucie-Smith E, Marie P, Mark L P, Soques A, Sternberg M, Toms K, Weinberg S J, Wells C   +20 more
core   +2 more sources

Impact of the diagnostic delay of acromegaly on bone health: data from a real life and long term follow-up experience

Pituitary, 2022
Acromegaly is a chronic disease with systemic complications. Disease onset is insidious and consequently typically burdened by diagnostic delay. A longer diagnostic delay induces more frequently cardiovascular, respiratory, metabolic, neuropsychiatric ...
S. Chiloiro, A. Giampietro, I. Gagliardi, M. Bondanelli, Miriam Veleno, M. Ambrosio, M. Zatelli, A. Pontecorvi, A. Giustina, L. De Marinis, Antonio Bianchi   +10 more
semanticscholar   +1 more source

Hyperglycemia induced by pasireotide in patients with Cushing’s disease or acromegaly [PDF]

, 2016
PURPOSE: Cushing’s disease (CD) and acromegaly are characterized by excessive hormone secretion resulting in comorbidities such as impaired glucose metabolism, diabetes and hypertension.
Silverstein, Julie M
core   +2 more sources

The Biochemical Diagnosis of Acromegaly

Journal of Clinical Medicine, 2021
Background: The diagnosis of acromegaly still poses a clinical challenge, and prolonged diagnostic delay is common. The most important assays for the biochemical diagnosis and management of acromegaly are growth hormone (GH) and insulin-like growth ...
A. Akirov, H. Masri-Iraqi, I. Dotan, I. Shimon   +3 more
semanticscholar   +1 more source

CONDITION OF THE MUSCULOSKELETAL SYSTEM IN PATIENTSWITH ACROMEGALY.

Остеопороз и остеопатии, 2010
Despite the relatively low incidence of acromegaly (60-70 cases per I million inhabitants), this disease has a special place among the heterogeneous group of diseases that lead to the defeat of the locomotor apparatus.
A S Fedotova, N N Molitvoslovova, L I Alekseeva, L Ya Rozhinskaya, A. S. Fedotova, N. N. Molitvoslovova, L. I. Alexeeva, L. Y. Rozhinskaya   +7 more
doaj   +1 more source

The role of stereotactic radiosurgery in the multimodal management of growth hormone–secreting pituitary adenomas [PDF]

, 2010
Growth hormone (GH)–secreting pituitary adenomas represent a common source of GH excess in patients with acromegaly. Whereas surgical extirpation of the culprit lesion is considered first-line treatment, as many as 19% of patients develop recurrent ...
Liu, Charles Y., Stapleton, Christopher J., Weiss, Martin H.   +2 more
core   +1 more source

Acromegaly: an endocrine society clinical practice guideline.

Journal of Clinical Endocrinology and Metabolism, 2014
OBJECTIVE The aim was to formulate clinical practice guidelines for acromegaly. PARTICIPANTS The Task Force included a chair selected by the Endocrine Society Clinical Guidelines Subcommittee (CGS), five experts in the field, and a methodologist.
L. Katznelson, E. Laws, S. Melmed, M. Molitch, M. Murad, A. Utz, J. Wass   +6 more
semanticscholar   +1 more source

Feline hypersomatotropism and acromegaly tumorigenesis: a potential role for the AIP gene [PDF]

, 2017
Acromegaly in humans is usually sporadic, however up to 20% of familial isolated pituitary adenomas are caused by germline sequence variants of the aryl-hydrocarbon-receptor interacting protein (AIP) gene.
Catchpole, B, Church, D B, Forcada, Y, Fowkes, R C, Niessen, S J M, Scudder, C J   +5 more
core   +2 more sources