Results 21 to 30 of about 23,277 (221)
Multiomics Approach to Acromegaly: Unveiling Translational Insights for Precision Medicine [PDF]
Endocrinology and Metabolism, 2023 The clinical characteristics and prognoses of acromegaly vary among patients. Assessment of current and novel predictors can lead to multilevel categorization of patients, allowing integration into new clinical guidelines and a reduction in the increased
Kyungwon Kim +2 more
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Acromegaly - Mortality, Morbidity and Treatment Patterns [PDF]
, 2022 Background: Acromegaly is a systemic disease associated with multiple comorbidities. The clinical characteristics of acromegaly develop insidiously over several years and the diagnosis is usually delayed.
Esposito, Daniela
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The Journal of Clinical Endocrinology & Metabolism, 1997 This review presents a collection of uncommon aspects of acromegaly based on extensive experience of the authors.
COLAO, ANNAMARIA +3 more
openaire +5 more sources
Ageing genetic signature of hypersomatotropism
Open Biology, 2021 Acromegaly is a pathological condition that is caused by over-secretion of growth hormone (GH) and develops primarily from a pituitary adenoma. Excess GH exposure over a prolonged period of time leads to a wide range of systemic manifestations and ...
Abdalla Elbialy
doaj +1 more source
Old Wine in a New Bottle: Acromegaly Presenting as Diabetic Ketoacidosis [PDF]
Journal of Clinical and Diagnostic Research, 2021 Acromegaly is a rare disease characterised by chronic excess of Growth Hormone (GH) levels. Insulin signalling is impaired, gluconeogenesis is excess and peripheral insulin resistance is increased in acromegaly causing hyperglycaemia and diabetes ...
Sowrabha Bhat +3 more
doaj +1 more source
Presence of cerebral microbleeds is associated with cognitive decline in acromegaly
Frontiers in Oncology, 2022 BackgroundCognitive decline in acromegaly has gained increasing attention. Cerebral microbleeds (CMBs) as radiographic markers for microvascular injury have been linked to various types of cognitive decline. However, the association between CMB formation
Zhengxing Xie +7 more
doaj +1 more source
Acromegaly: Clinical Care in Central and Eastern Europe, Israel, and Kazakhstan
Frontiers in Endocrinology, 2022 Acromegaly is a rare condition typically caused by benign pituitary adenomas, resulting in excessive production of growth hormone. Clinical manifestations of acromegaly are diverse, varying from the overgrowth of body tissue to cardiovascular, metabolic,
Marek Bolanowski +17 more
doaj +1 more source
Is H19 RNA a Useful Marker of Acromegaly and Its Complications? A Preliminary Study
Biomedicines, 2023 Acromegaly is a rare endocrine disorder caused by somatotroph pituitary adenoma. Besides its typical symptoms, it contributes to the development of cardiovascular, metabolic, and bone comorbidities. H19 RNA is a long non-coding RNA and it is suspected to
Małgorzata Rolla +4 more
doaj +1 more source
Skeletal complications in acromegaly
, 2023 Hypersecretion of growth hormone (GH) is rare and typically results from a pituitary functional tumor – somatotropinoma. It leads to excessive linear bone growth and manifests as gigantism if occurring in childhood and adolescence, before the closure of ...
Arnika Wydra +2 more
core +1 more source