Results 21 to 30 of about 24,454 (211)
Endocrinology and Metabolism Clinics of North America, 2001 Acromegaly is a slow developing disease caused by hypersecretion of growth hormone and insulin-like growth factor 1. Increased morbidity and mortality associated with the disease make early diagnosis and treatment crucial. This article reviews the etiology, clinical manifestations, and diagnosis of acromegaly, with an emphasis on newly available ...
Anat, Ben-Shlomo, Shlomo, Melmed
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Frontiers in Endocrinology, 2022 Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are essential to normal growth, metabolism, and body composition, but in acromegaly, excesses of these hormones strikingly alter them.
Pamela U. Freda
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Multiomics Approach to Acromegaly: Unveiling Translational Insights for Precision Medicine [PDF]
Endocrinology and Metabolism, 2023 The clinical characteristics and prognoses of acromegaly vary among patients. Assessment of current and novel predictors can lead to multilevel categorization of patients, allowing integration into new clinical guidelines and a reduction in the increased
Kyungwon Kim +2 more
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Prevalence and risk factors of sleep breathing disorders in patients with acromegaly from Moscow region [PDF]
Терапевтический архив, 2018 Aim. Assessment of prevalence and risk factors of sleep breathing disorders in patients with acromegaly from Moscow region. Materials and methods. Cardiorespiratory monitoring was executed to 55 patients with acromegaly (18 men and 37 women): 27 patients
Yu A Kovaleva +4 more
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Ageing genetic signature of hypersomatotropism
Open Biology, 2021 Acromegaly is a pathological condition that is caused by over-secretion of growth hormone (GH) and develops primarily from a pituitary adenoma. Excess GH exposure over a prolonged period of time leads to a wide range of systemic manifestations and ...
Abdalla Elbialy
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Old Wine in a New Bottle: Acromegaly Presenting as Diabetic Ketoacidosis [PDF]
Journal of Clinical and Diagnostic Research, 2021 Acromegaly is a rare disease characterised by chronic excess of Growth Hormone (GH) levels. Insulin signalling is impaired, gluconeogenesis is excess and peripheral insulin resistance is increased in acromegaly causing hyperglycaemia and diabetes ...
Sowrabha Bhat +3 more
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Presence of cerebral microbleeds is associated with cognitive decline in acromegaly
Frontiers in Oncology, 2022 BackgroundCognitive decline in acromegaly has gained increasing attention. Cerebral microbleeds (CMBs) as radiographic markers for microvascular injury have been linked to various types of cognitive decline. However, the association between CMB formation
Zhengxing Xie +7 more
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Acromegaly: Clinical Care in Central and Eastern Europe, Israel, and Kazakhstan
Frontiers in Endocrinology, 2022 Acromegaly is a rare condition typically caused by benign pituitary adenomas, resulting in excessive production of growth hormone. Clinical manifestations of acromegaly are diverse, varying from the overgrowth of body tissue to cardiovascular, metabolic,
Marek Bolanowski +17 more
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QJM: An International Journal of Medicine, 2016 Abstract Acromegaly is a rare, chronic, progressive disease characterized by an excess secretion of growth hormone (GH) and increased circulating insulin-like growth factor 1 (IGF-1) concentrations. It is caused by a pituitary adenoma in the vast majority of cases.
R, Dineen, P M, Stewart, M, Sherlock
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Is H19 RNA a Useful Marker of Acromegaly and Its Complications? A Preliminary Study
Biomedicines, 2023 Acromegaly is a rare endocrine disorder caused by somatotroph pituitary adenoma. Besides its typical symptoms, it contributes to the development of cardiovascular, metabolic, and bone comorbidities. H19 RNA is a long non-coding RNA and it is suspected to
Małgorzata Rolla +4 more
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