Results 11 to 20 of about 23,277 (221)
Nature Reviews Disease Primers, 2019 Acromegaly is characterized by increased release of growth hormone and, consequently, insulin-like growth factor I (IGF1), most often by a pituitary adenoma. Prolonged exposure to excess hormone leads to progressive somatic disfigurement and a wide range of systemic manifestations that are associated with increased mortality. Although considered a rare
Colao A. +6 more
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Frontiers in Endocrinology, 2022 Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are essential to normal growth, metabolism, and body composition, but in acromegaly, excesses of these hormones strikingly alter them.
Pamela U. Freda
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Trends in Endocrinology & Metabolism, 1992 In the majority of cases, acromegaly is due to GH hypersecretion by a somatotroph pituitary tumor. The etiology of acromegaly is not known, and may be related to GHRH hypersecretion, intrinsic pituitary defect, or a combination thereof. Recent physiologic data and molecular biology techniques provide insights into the pathophysiology of this condition.
Barkan, Ariel L.
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Reproductive Biology and EndocrinologyContext Acromegaly is a rare disease caused by excessive growth hormone (GH) secretion, mostly induced by pituitary adenomas. The care of pregnant women with acromegaly is challenging, in part due to existing clinical data being limited and not entirely ...
Anke Tönjes +11 more
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Executive functioning and quality of life in acromegaly
Psychology Research and Behavior Management, 2019 Emilia Solomon,1,2 Dumitru Brănișteanu,1,3 Andrei Dumbravă,4 Radu Gheorghe Solomon,5 Lorànt Kiss,5 Mihai Glod,1 Cristina Preda1,3 1Faculty of Medicine, Grigore T.
Solomon E +6 more
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Alʹmanah Kliničeskoj Mediciny, 2017 Acromegaly is a rare disease with increased growth hormone secretion most often caused by pituitary adenoma. Not adequately treated acromegaly may lead to early death related to increased rates of acute cardiovascular events, sleep apnea, metabolic ...
I. D. Chikh +3 more
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Can acromegaly be controlled in all cases? [PDF]
J NeuroendocrinolAbstract Acromegaly is a rare disease, due in most of the cases to a growth hormone (GH)‐secreting pituitary adenoma (PA), namely neuroendocrine tumour (PitNET). The treatment of patients with acromegaly is multimodal and multi‐step, including surgery, medical therapies, and radiotherapy.
Chiloiro S +14 more
europepmc +2 more sources
Association of Epicardial Adipose Tissue Thickness with Cardiovascular Risk in Acromegaly
Medeniyet Medical Journal, 2022 Objective: Acromegaly is a rare disease associated with increased mortality. Reports on coronary artery disease in acromegaly are controversial. This study aimed to investigate the possible association of epicardial adipose tissue thickness with ...
Bulent CAN +3 more
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Endocrinology and Metabolism Clinics of North America, 2001 Acromegaly is a slow developing disease caused by hypersecretion of growth hormone and insulin-like growth factor 1. Increased morbidity and mortality associated with the disease make early diagnosis and treatment crucial. This article reviews the etiology, clinical manifestations, and diagnosis of acromegaly, with an emphasis on newly available ...
Anat, Ben-Shlomo, Shlomo, Melmed
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Prevalence and risk factors of sleep breathing disorders in patients with acromegaly from Moscow region [PDF]
Терапевтический архив, 2018 Aim. Assessment of prevalence and risk factors of sleep breathing disorders in patients with acromegaly from Moscow region. Materials and methods. Cardiorespiratory monitoring was executed to 55 patients with acromegaly (18 men and 37 women): 27 patients
Yu A Kovaleva +4 more
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