Results 51 to 60 of about 49,296 (268)
Acromegaly without acral anomalies [PDF]
Romanian Journal of Medical Practice, 2021 Early recognition of a pituitary secretor tumor offers a better prognostic; thus acromegaly might be recognized before the actual clinical picture of acromegaly is detectable.
Mara Carsote +6 more
doaj +1 more source
Parathyroid localization [PDF]
, 1986 Twenty-nine consecutive patients with suspected primary hyperparathyroidism were examined preoperatively using ultrasound, sonographically guided fine needle aspiration, and aspirate immunostaining for PTH.
Borisch, B. +7 more
core +1 more source
Complications and Comorbidities of Acromegaly—Retrospective Study in Polish Center
Frontiers in Endocrinology, 2021 Introduction In acromegaly, chronic exposure to impaired GH and IGF-I levels leads to the development of typical acromegaly symptoms, and multiple systemic complications as cardiovascular, metabolic, respiratory, endocrine, and bone disorders. Acromegaly
M. Rolla +7 more
semanticscholar +1 more source
Extra-hepatic Acromegaly [PDF]
US Endocrinology, 2010 After the introduction of somatostatin analogs (LA-SMSA) and the growth hormone (GH) receptor antagonist, pegvisomant (Peg-v) normal serum insulin-like growth factor-1 (IGF-1) concentrations in virtually every patients with acromegaly is possible. The impact of these products on the GH–IGF1 axis is completely different.
Franck, Sanne E. +2 more
openaire +3 more sources
Frontiers in Endocrinology, 2019 Introduction: The vitamin D receptor (VDR) gene is one of the most widely studied tumorigenesis-related genes. The primary objective of this study was assessment of possible roles of VDR gene polymorphisms in acromegaly, with regard to the activity of ...
Aleksandra Jawiarczyk-Przybyłowska +5 more
doaj +1 more source
Rheumatic manifestations of acromegaly [PDF]
Остеопороз и остеопатии, 2020 Acromegaly is a chronic endocrine disease characterized by excessive secretion of growth hormone (GH), which, in turn, leads to increased insulin-like growth factor 1 (IGF-1) secretion by the liver.
Taras S. Panevin +2 more
doaj +1 more source
Systemic Complications of Acromegaly and the Impact of the Current Treatment Landscape: An Update.
Endocrine reviews, 2018 Acromegaly is a chronic systemic disease with many complications and is associated with increased mortality when not adequately treated. Substantial advances in acromegaly treatment, as well as in the treatment of many of its complications, mainly ...
M. Gadelha +3 more
semanticscholar +1 more source
Bone densitometry by radiofrequency echographic multi-spectrometry (REMS) in acromegaly patients
Endokrynologia Polska, 2020 INTRODUCTION: Radiofrequency echographic multi-spectrometry (REMS) is a recently introduced non-ionising technology employed in the evaluation of osteoporosis.
Małgorzata Rolla +3 more
doaj +1 more source
Growth Hormone (GH)-Releasing Peptide Stimulation of GH Release from Human Somatotroph Adenoma Cells: Interaction with GH-Releasing Hormone, Thyrotropin- Releasing Hormone, and Octreotide. [PDF]
, 1994 The synthetic hexapeptide GH-releasing peptide (GHRP; His-D-Trp-Ala-Trp-D-Phe-Lys-NH2) specifically stimulates GH secretion in humans in vivo and in animals in vitro and in vivo via a still unknown receptor and mechanism.
Brockmeier, S. +7 more
core +1 more source
Trends in Endocrinology & Metabolism, 1992 In the majority of cases, acromegaly is due to GH hypersecretion by a somatotroph pituitary tumor. The etiology of acromegaly is not known, and may be related to GHRH hypersecretion, intrinsic pituitary defect, or a combination thereof. Recent physiologic data and molecular biology techniques provide insights into the pathophysiology of this condition.
openaire +3 more sources