Results 51 to 60 of about 24,454 (211)

Real-world burden of disease, treatment, and healthcare resource utilization in acromegaly: a quantitative survey of patient experiences

Journal of Patient-Reported Outcomes
Background Acromegaly is a rare endocrine disease caused by excessive growth hormone (GH) secretion typically due to a pituitary adenoma. Patients ineligible for or with an inadequate response to surgery and/or radiotherapy often require pharmacotherapy ...
Maxwell Koobatian, Jill Sisco, Janetricks C. Okeyo, Alan Krasner, Tiffany P. Quock   +4 more
doaj   +1 more source

Biomarkers of acromegaly [PDF]

Endocrine, 2015
The papers of Kiseljak-Vassiliades et al. [1] and Selek et al. [2] published in this issue are significant because they focus on an important and unresolved problem of pituitary tumor prognosis, progression, and treatment. Many years ago, pituitary tumors were classified based only on their tinctorial properties using the hematoxylin—eosin stain and ...
Luis V, Syro, Fabio, Rotondo, Kalman, Kovacs   +2 more
openaire   +2 more sources

A Cross‐Species Hormone Knowledge Base With Multi‐Dimensional Data Integration and Intelligent Query Assistance

iMetaMed, EarlyView.
AHormoneDB is a no‐code platform that combines DOID‐standardized hormone–disease associations, regulatory prediction, and retrieval‐augmented generation‐based querying. In acromegaly, it nominated PTPN1 as a previously underappreciated candidate, demonstrating its capacity to accelerate mechanistic discovery.
Xingxing Huang, Yulong Bai, Jinfei Zhang, Lihong Zhang, Yongqiang Xing, Zhihui Zhang, Yuanping Lu   +6 more
wiley   +1 more source

Standing Balance Control in Patients with Acromegaly

, 2023
Patients with acromegaly (PWA) experience higher rates of falls and fall-related injuries than Canadian older adults. Therefore, the aim of the present study was to determine if acromegaly influenced the control of standing balance. Bipedal and unipedal
Title, Michaela
core  

Serum Levels of Asprosin, a Novel Adipokine, Are Significantly Lowered in Patients with Acromegaly

International Journal of Endocrinology, 2020
Background. Asprosin is a novel identified adipokine secreted mainly by white adipose tissue, which is elevated in metabolic diseases such as diabetes and obesity.
Xiaoan Ke, Lian Duan, Fengying Gong, Yuelun Zhang, Kan Deng, Yong Yao, Linjie Wang, Hui Pan, Huijuan Zhu   +8 more
doaj   +1 more source

Paediatric Melanonychia: Diagnosis and Management

JEADV Clinical Practice, EarlyView.
ABSTRACT Longitudinal melanonychia (LM) in children presents unique diagnostic and management challenges that cannot be adequately addressed by applying adult‐based criteria. Unlike in adults, there are no validated clinical, dermoscopic or histopathologic criteria for predicting nail unit melanoma in the paediatric population.
Angela J. Jiang, Erika Koh, Je‐Ho Mun, Dong‐Youn Lee, Matilde Iorizzo, Adam I. Rubin   +5 more
wiley   +1 more source

Guidelines on diagnostics and treatment of acromegaly (draft)

Ожирение и метаболизм
We recommend acromegaly to be ruled in all patients with characteristic changes in appearance (A3). In all patients without characteristic changes in appearance, we recommend to rule out acromegaly, if several clinical signs suspicious for acromegaly are
E. G. Przhiyalkovskaya, N. G. Mokrysheva, E. A. Troshina, G. A. Melnichenko, I. I. Dedov, M. B. Antsiferov, L. I. Astafieva, T. P. Bardymova, Zh. E. Belaya, G. R. Vagapova, S. Yu. Vorotnikova, A. Yu. Grigoriev, E. N. Grineva, L. K. Dzeranova, I. A. Ilovaiskaya, P. L. Kalinin, A. M. Lapshina, A. S. Lutsenko, E. O. Mamedova, E. I. Marova, M. A. Perepelova, E. A. Pigarova, V. S. Pronin, L. Ya. Rozhinskaya, Yu. Yu. Trunin, A. S. Shutova   +25 more
doaj   +1 more source

Hypertension and Acromegaly [PDF]

Endocrinology and Metabolism Clinics of North America, 2019
Hypertension is one of the most frequent complications in acromegaly, with a median frequency of 33.6% (range, 11%-54.7%). Although the pathogenesis has not been fully elucidated, it probably results from concomitant factors leading to expansion of extracellular fluid volume, increase of peripheral vascular resistance, and development of sleep apnea ...
Puglisi S, Terzolo M
openaire   +3 more sources

Bibliometric Analysis of Research on Pituitary Adenomas: Recent Progress in Pathogenesis and Clinical Management

Medicine Advances, EarlyView.
A bibliometric analysis of 15,418 publications mapped global research on pituitary adenomas and identified 6 major research themes. Keyword trends highlighted the growing prominence of artificial intelligence‐related research. ABSTRACT Background Pituitary adenomas (PAs) comprise most of the tumors that originate from the sellar region.
Zhengyang Shen, Kan Deng, Lin Lu, Jifang Liu, Zhang Ye, Yi Zhang, Yong Yao   +6 more
wiley   +1 more source

Acromegaly with metastatic renal cell carcinoma: Lung, gluteal and scapular metastasis

Medicine Science, 2018
The association between acromegaly and increased incidence of malignancy has been reported due to high GH and IGF levels. Although the incidence of all malignancies increases in patients with acromegaly, renal cell carcinoma (RCC) has been rarely ...
Ziynet Alphan Uc, Ozgur Demir, Suheyla Gorar, Sevim Gullu   +3 more
doaj   +1 more source